| Reaction Details |
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 | Report a problem with these data |
| Target | Suppressor of tumorigenicity 14 protein homolog |
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| Ligand | BDBM50135274 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1544368 (CHEMBL3748444) |
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| Ki | 227±n/a nM |
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| Citation |  Kwon, H; Kim, Y; Park, K; Choi, SA; Son, SH; Byun, Y Structure-based design, synthesis, and biological evaluation of Leu-Arg dipeptide analogs as novel hepsin inhibitors. Bioorg Med Chem Lett26:310-4 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Suppressor of tumorigenicity 14 protein homolog |
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| Name: | Suppressor of tumorigenicity 14 protein homolog |
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| Synonyms: | Epithin | Prss14 | ST14_MOUSE | Serine protease 14 | St14 | Suppressor of tumorigenicity 14 protein homolog |
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| Type: | PROTEIN |
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| Mol. Mass.: | 94658.46 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_116697 |
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| Residue: | 855 |
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| Sequence: | MGSNRGRKAGGGSQDFGAGLKYNSRLENMNGFEEGVEFLPANNAKKVEKRGPRRWVVLVA
VLFSFLLLSLMAGLLVWHFHYRNVRVQKVFNGHLRITNEIFLDAYENSTSTEFISLASQV
KEALKLLYNEVPVLGPYHKKSAVTAFSEGSVIAYYWSEFSIPPHLAEEVDRAMAVERVVT
LPPRARALKSFVLTSVVAFPIDPRMLQRTQDNSCSFALHAHGAAVTRFTTPGFPNSPYPA
HARCQWVLRGDADSVLSLTFRSFDVAPCDEHGSDLVTVYDSLSPMEPHAVVRLCGTFSPS
YNLTFLSSQNVFLVTLITNTDRRHPGFEATFFQLPKMSSCGGFLSDTQGTFSSPYYPGHY
PPNINCTWNIKVPNNRNVKVRFKLFYLVDPNVPVGSCTKDYVEINGEKYCGERSQFVVSS
NSSKITVHFHSDHSYTDTGFLAEYLSYDSNDPCPGMFMCKTGRCIRKELRCDGWADCPDY
SDERYCRCNATHQFTCKNQFCKPLFWVCDSVNDCGDGSDEEGCSCPAGSFKCSNGKCLPQ
SQKCNGKDNCGDGSDEASCDSVNVVSCTKYTYRCQNGLCLSKGNPECDGKTDCSDGSDEK
NCDCGLRSFTKQARVVGGTNADEGEWPWQVSLHALGQGHLCGASLISPDWLVSAAHCFQD
DKNFKYSDYTMWTAFLGLLDQSKRSASGVQELKLKRIITHPSFNDFTFDYDIALLELEKS
VEYSTVVRPICLPDATHVFPAGKAIWVTGWGHTKEGGTGALILQKGEIRVINQTTCEDLM
PQQITPRMMCVGFLSGGVDSCQGDSGGPLSSAEKDGRMFQAGVVSWGEGCAQRNKPGVYT
RLPVVRDWIKEHTGV
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| BDBM50135274 |
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| n/a |
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| Name | BDBM50135274 |
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| Synonyms: | CHEMBL404190 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H30N6O3S |
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| Mol. Mass. | 446.566 |
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| SMILES | [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](-[#6])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-c1nc2ccccc2s1 |
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| Structure | 
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