| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase Nek6 |
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| Ligand | BDBM50144963 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1556161 (CHEMBL3768615) |
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| Kd | 130±n/a nM |
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| Citation |  Min, J; Guo, K; Suryadevara, PK; Zhu, F; Holbrook, G; Chen, Y; Feau, C; Young, BM; Lemoff, A; Connelly, MC; Kastan, MB; Guy, RK Optimization of a Novel Series of Ataxia-Telangiectasia Mutated Kinase Inhibitors as Potential Radiosensitizing Agents. J Med Chem59:559-77 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase Nek6 |
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| Name: | Serine/threonine-protein kinase Nek6 |
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| Synonyms: | NEK kinase | NEK6 | NEK6_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35724.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1446777 |
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| Residue: | 313 |
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| Sequence: | MAGQPGHMPHGGSSNNLCHTLGPVHPPDPQRHPNTLSFRCSLADFQIEKKIGRGQFSEVY
KATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNI
VLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFI
TATGVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEM
AALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCICPDPHQRPDIGYVH
QVAKQMHIWMSST
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| BDBM50144963 |
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| n/a |
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| Name | BDBM50144963 |
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| Synonyms: | CHEMBL3763358 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H19N7O3 |
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| Mol. Mass. | 393.3993 |
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| SMILES | COCCOc1cc2c(ncnc2cc1OC)-n1nc(nc1N)-c1ccccn1 |
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| Structure | 
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