| Reaction Details |
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 | Report a problem with these data |
| Target | Transmembrane domain-containing protein TMIGD3 |
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| Ligand | BDBM50074225 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1556380 (CHEMBL3772111) |
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| Ki | 19±n/a nM |
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| Citation |  Donegan, RK; Lieberman, RL Discovery of Molecular Therapeutics for Glaucoma: Challenges, Successes, and Promising Directions. J Med Chem59:788-809 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transmembrane domain-containing protein TMIGD3 |
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| Name: | Transmembrane domain-containing protein TMIGD3 |
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| Synonyms: | TMIG3_HUMAN | TMIGD3 | Transmembrane domain-containing protein TMIGD3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30335.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_114868 |
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| Residue: | 266 |
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| Sequence: | MEGSPAGPIEQKEARWESSWEEQPDWTLGCLSPESQFRIPGLPGCILSFQLKVCFLPVMW
LFILLSLALISDAMVMDEKVKRSFVLDTASAICNYNAHYKNHPKYWCRGYFRDYCNIIAF
SPNSTNHVALRDTGNQLIVTMSCLTKEDTGWYWCGIQRDFARDDMDFTELIVTDDKGTLA
NDFWSGKDLSGNKTRSCKAPKVVRKADRSRTSILIICILITGLGIISVISHLTKRRRSQR
NRRVGNTLKPFSRVLTPKEMAPTEQM
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| BDBM50074225 |
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| n/a |
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| Name | BDBM50074225 |
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| Synonyms: | 6-Ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propyl-nicotinic acid propyl ester | CHEMBL111545 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H29NO3S |
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| Mol. Mass. | 399.546 |
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| SMILES | CCCOC(=O)c1c(CCC)c(C(=O)SCC)c(CC)nc1-c1ccccc1 |
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| Structure | 
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