| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-galactosidase |
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| Ligand | BDBM50358321 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1558582 (CHEMBL3774071) |
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| Ki | 870±n/a nM |
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| Citation |  Thonhofer, M; Weber, P; Santana, AG; Fischer, R; Pabst, BM; Paschke, E; Schalli, M; Stütz, AE; Tschernutter, M; Windischhofer, W; Withers, SG Synthesis of C-5a-chain extended derivatives of 4-epi-isofagomine: Powerfulß-galactosidase inhibitors and low concentration activators of GM1-gangliosidosis-related human lysosomalß-galactosidase. Bioorg Med Chem Lett26:1438-42 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-galactosidase |
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| Name: | Beta-galactosidase |
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| Synonyms: | β-galactosidase | BGAL_BOVIN | Beta-galactosidase/Glucosylceramidase | GLB1 |
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| Type: | Protein |
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| Mol. Mass.: | 73420.88 |
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| Organism: | Bos taurus (Bovine) |
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| Description: | n/a |
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| Residue: | 653 |
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| Sequence: | MPGVVRLLALLLVPLLLGSARGLHNATQRTFQIDYRRNRFLKDGQPFRYISGSIHYFRVP
RFYWKDRLLKMKMAGLNAIQTYVAWNFHELQPGRYNFSGDHDVEHFIQLAHELGLLVILR
PGPYICAEWDMGGLPAWLLEKKSIVLRSSDPDYLAAVDKWLGVLLPKMRPLLYKNGGPII
TVQVENEYGSYLSCDYDYLRFLQKRFHDHLGEDVLLFTTDGVNERLLQCGALQGLYATVD
FSPGTNLTAAFMLQRKFEPTGPLVNSEFYTGWLDHWGQRHSTVSSKAVAFTLHDMLALGA
NVNMYMFIGGTNFAYWNGANIPYQPQPTSYDYDAPLSEAGDLTEKYFALRDIIQKFAKVP
EGPIPPSTPKFAYGKVALNKLKTVEDALNILCPSGPIKSVYPLTFIDVKQYFGFVLYRTM
LPEDCSDPTPLSSPLSGVHDRAYVSVNGVAQGILERESVITLNITGKAGATLDLLVENMG
RVNYGSSINDFKGLVSNLTLGSKILTNWEIFPLDMEDAVRSHLGTWGGRDRGYHNKARAH
SPPTYALPTFYVGNFTIPSGIADLPQDTFIQFPGWTKGQVWINGFNLGRYWPVRGPQMTL
FVPQHILVTSTPNTIVVLELEHAPCQDGGPELCTVEFVDKPVFRTVQTHRHAN
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| BDBM50358321 |
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| n/a |
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| Name | BDBM50358321 |
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| Synonyms: | CHEMBL1922579 | CHEMBL1922581 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H29NO4 |
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| Mol. Mass. | 287.3951 |
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| SMILES | CCCCCCCCN[C@@H]1C=C(CO)[C@H](O)[C@H](O)[C@H]1O |r,t:10| |
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| Structure | 
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