| Reaction Details |
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 | Report a problem with these data |
| Target | N-acylethanolamine-hydrolyzing acid amidase |
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| Ligand | BDBM50151148 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1558879 |
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| IC50 | 130±n/a nM |
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| Citation |  Nuzzi, A; Fiasella, A; Ortega, JA; Pagliuca, C; Ponzano, S; Pizzirani, D; Bertozzi, SM; Ottonello, G; Tarozzo, G; Reggiani, A; Bandiera, T; Bertozzi, F; Piomelli, D Potenta-amino-ß-lactam carbamic acid ester as NAAA inhibitors. Synthesis and structure-activity relationship (SAR) studies. Eur J Med Chem111:138-59 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| N-acylethanolamine-hydrolyzing acid amidase |
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| Name: | N-acylethanolamine-hydrolyzing acid amidase |
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| Synonyms: | ASAH-like protein | ASAHL | Acid ceramidase-like protein | N-acylethanolamine-hydrolyzing acid amidase | N-acylsphingosine amidohydrolase-like | N-acylsphingosine-amidohydrolase | NAAA | NAAA_HUMAN | PLT |
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| Type: | Enzyme |
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| Mol. Mass.: | 40073.12 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q02083 |
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| Residue: | 359 |
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| Sequence: | MRTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLV
RAAMAQVIGDRVPKWVHVLIGKVVLELERFLPQPFTGEIRGMCDFMNLSLADCLLVNLAY
ESSVFCTSIVAQDSRGHIYHGRNLDYPFGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGL
WTGQSPHKFTVSGDERDKGWWWENAIAALFRRHIPVSWLIRATLSESENFEAAVGKLAKT
PLIADVYYIVGGTSPREGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDR
RTSAIKALNATGQANLSLEALFQILSVVPVYNNFTIYTTVMSAGSPDKYMTRIRNPSRK
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| BDBM50151148 |
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| n/a |
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| Name | BDBM50151148 |
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| Synonyms: | CHEMBL3769700 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H16N2O3 |
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| Mol. Mass. | 260.2884 |
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| SMILES | O=C(N[C@H]1CNC1=O)OCc1ccc2CCCc2c1 |r| |
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| Structure | 
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