| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 2, facilitated glucose transporter member 1 |
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| Ligand | BDBM50152823 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1565336 |
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| IC50 | 53±n/a nM |
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| Citation |  Siebeneicher, H; Bauser, M; Buchmann, B; Heisler, I; Müller, T; Neuhaus, R; Rehwinkel, H; Telser, J; Zorn, L Identification of novel GLUT inhibitors. Bioorg Med Chem Lett26:1732-7 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 2, facilitated glucose transporter member 1 |
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| Name: | Solute carrier family 2, facilitated glucose transporter member 1 |
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| Synonyms: | GLUT-1 | GLUT1 | GTR1_HUMAN | Glucose Transporter 1 (hGLUT1) | Glucose transporter | Glucose transporter type 1, erythrocyte/brain | HepG2 glucose transporter | SLC2A1 |
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| Type: | Protein |
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| Mol. Mass.: | 54091.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 492 |
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| Sequence: | MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTT
LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE
MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM
GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD
LQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK
AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ
LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM
CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE
ELFHPLGADSQV
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| BDBM50152823 |
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| n/a |
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| Name | BDBM50152823 |
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| Synonyms: | CHEMBL3780054 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22N6O2 |
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| Mol. Mass. | 402.4491 |
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| SMILES | COc1ccccc1N1CCN(CC1)c1ncnc2n(-c3ccccc3)c(=O)[nH]c12 |
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| Structure | 
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