| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Solute carrier family 2, facilitated glucose transporter member 2 |
|---|
| Ligand | BDBM50152746 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1565337 (CHEMBL3782731) |
|---|
| IC50 | >10000±n/a nM |
|---|
| Citation |  Siebeneicher, H; Bauser, M; Buchmann, B; Heisler, I; Müller, T; Neuhaus, R; Rehwinkel, H; Telser, J; Zorn, L Identification of novel GLUT inhibitors. Bioorg Med Chem Lett26:1732-7 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Solute carrier family 2, facilitated glucose transporter member 2 |
|---|
| Name: | Solute carrier family 2, facilitated glucose transporter member 2 |
|---|
| Synonyms: | GLUT2 | GTR2_HUMAN | SLC2A2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 57494.38 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_599700 |
|---|
| Residue: | 524 |
|---|
| Sequence: | MTEDKVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYV
INSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGD
TLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIA
PTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCP
ESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSY
RQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLV
EKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPW
FMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFT
FFKVPETKGKSFEEIAAEFQKKSGSAHRPKAAVEMKFLGATETV
|
|
|
|---|
| BDBM50152746 |
|---|
| n/a |
|---|
| Name | BDBM50152746 |
|---|
| Synonyms: | CHEMBL3780119 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H22N6O |
|---|
| Mol. Mass. | 398.4604 |
|---|
| SMILES | [H][C@@]12CN(c3ncnc4n(ncc34)-c3ccccc3)[C@@]([H])(CN1c1ccccc1OC)C2 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
