| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor alpha |
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| Ligand | BDBM50152829 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1563454 (CHEMBL3783047) |
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| IC50 | 20±n/a nM |
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| Citation |  Flick, AC; Ding, HX; Leverett, CA; Kyne, RE; Liu, KK; Fink, SJ; O'Donnell, CJ Synthetic approaches to the 2014 new drugs. Bioorg Med Chem24:1937-80 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor alpha |
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| Name: | Peroxisome proliferator-activated receptor alpha |
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| Synonyms: | NR1C1 | Nuclear receptor subfamily 1 group C member 1 | PPAR | PPAR alpha/gamma | PPAR-alpha | PPARA | PPARA_HUMAN | Peroxisome Proliferator-Activated Receptor alpha | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor alpha (PPAR alpha) |
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| Type: | Enzyme |
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| Mol. Mass.: | 52222.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q07869 |
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| Residue: | 468 |
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| Sequence: | MVDTESPLCPLSPLEAGDLESPLSEEFLQEMGNIQEISQSIGEDSSGSFGFTEYQYLGSC
PGSDGSVITDTLSPASSPSSVTYPVVPGSVDESPSGALNIECRICGDKASGYHYGVHACE
GCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSE
KAKLKAEILTCEHDIEDSETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFV
IHDMETLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANL
DLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFD
FAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDI
FLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDMY
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| BDBM50152829 |
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| n/a |
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| Name | BDBM50152829 |
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| Synonyms: | CHEMBL3780740 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H26N4O9S2 |
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| Mol. Mass. | 578.615 |
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| SMILES | OS(O)(=O)=O.COc1ccc(Oc2cc(ncn2)N(C)CCOc2ccc(CC3SC(=O)NC3=O)cc2)cc1 |
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| Structure | 
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