| Reaction Details |
|---|
 | Report a problem with these data |
| Target | B2 bradykinin receptor |
|---|
| Ligand | BDBM50153658 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1561510 (CHEMBL3776147) |
|---|
| IC50 | 20000±n/a nM |
|---|
| Citation |  Scott, JS; Bailey, A; Davies, RD; Degorce, SL; MacFaul, PA; Gingell, H; Moss, T; Norman, RA; Pink, JH; Rabow, AA; Roberts, B; Smith, PD Tetrahydroisoquinoline Phenols: Selective Estrogen Receptor Downregulator Antagonists with Oral Bioavailability in Rat. ACS Med Chem Lett7:94-9 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| B2 bradykinin receptor |
|---|
| Name: | B2 bradykinin receptor |
|---|
| Synonyms: | B2 BRADYKININ | B2 bradykinin receptor | B2R | BDKRB2 | BK-2 receptor | BKR2 | BKRB2_HUMAN | Bradykinin B2 receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 44467.17 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | B2 BRADYKININ BDKRB2 HUMAN::P30411 |
|---|
| Residue: | 391 |
|---|
| Sequence: | MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQ
PPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNN
FDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLV
IWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSVI
TFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGI
LSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEP
IQMENSMGTLRTSISVERQIHKLQDWAGSRQ
|
|
|
|---|
| BDBM50153658 |
|---|
| n/a |
|---|
| Name | BDBM50153658 |
|---|
| Synonyms: | CHEMBL3775378 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H27NO3 |
|---|
| Mol. Mass. | 365.4654 |
|---|
| SMILES | CC(C)CN1[C@H](C)Cc2cc(O)ccc2[C@H]1c1ccc(\C=C\C(O)=O)cc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
