| Reaction Details |
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 | Report a problem with these data |
| Target | Pannexin-1 |
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| Ligand | BDBM50206509 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1564791 (CHEMBL3784394) |
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| IC50 | 150000±n/a nM |
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| Citation |  Baldwin, AG; Brough, D; Freeman, S Inhibiting the Inflammasome: A Chemical Perspective. J Med Chem59:1691-710 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Pannexin-1 |
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| Name: | Pannexin-1 |
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| Synonyms: | MRS1 | PANX1 | PANX1_HUMAN | Pannexin-1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48047.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_116759 |
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| Residue: | 426 |
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| Sequence: | MAIAQLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISI
GTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILL
YLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSARDLDMRDGACSVPGVTENLG
QSLWEVSESHFKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSL
SDEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFR
QKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKSSGQG
IDPMLLLTNLGMIKMDVVDGKTPMSAEMREEQGNQTAELQGMNIDSETKANNGEKNARQR
LLDSSC
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| BDBM50206509 |
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| n/a |
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| Name | BDBM50206509 |
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| Synonyms: | 4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfamoyl-benzoic acid anion | 4-Dipropylsulfamoyl-benzoic acid(probenecid) | Benemid | CHEMBL897 | PROBENECID | Probalan |
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| Type | Small organic molecule |
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| Emp. Form. | C13H19NO4S |
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| Mol. Mass. | 285.359 |
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| SMILES | CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O |
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| Structure | 
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