| Reaction Details |
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 | Report a problem with these data |
| Target | Hepatocyte growth factor activator |
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| Ligand | BDBM50071945 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1565754 (CHEMBL3782552) |
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| Ki | 54600±n/a nM |
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| Citation |  Venukadasula, PK; Owusu, BY; Bansal, N; Ross, LJ; Hobrath, JV; Bao, D; Truss, JW; Stackhouse, M; Messick, TE; Klampfer, L; Galemmo, RA Design and Synthesis of Nonpeptide Inhibitors of Hepatocyte Growth Factor Activation. ACS Med Chem Lett7:177-81 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Hepatocyte growth factor activator |
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| Name: | Hepatocyte growth factor activator |
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| Synonyms: | HGF activator | HGFA | HGFAC | HGFA_HUMAN | Hepatocyte growth factor activator | Hepatocyte growth factor activator long chain | Hepatocyte growth factor activator short chain |
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| Type: | PROTEIN |
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| Mol. Mass.: | 70690.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109514 |
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| Residue: | 655 |
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| Sequence: | MGRWAWVPSPWPPPGLGPFLLLLLLLLLLPRGFQPQPGGNRTESPEPNATATPAIPTILV
TSVTSETPATSAPEAEGPQSGGLPPPPRAVPSSSSPQAQALTEDGRPCRFPFRYGGRMLH
ACTSEGSAHRKWCATTHNYDRDRAWGYCVEATPPPGGPAALDPCASGPCLNGGSCSNTQD
PQSYHCSCPRAFTGKDCGTEKCFDETRYEYLEGGDRWARVRQGHVEQCECFGGRTWCEGT
RHTACLSSPCLNGGTCHLIVATGTTVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVAST
SASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWE
YCRLEACESLTRVQLSPDLLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHP
WLAAIYIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIE
KYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGW
GHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGG
PLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRIRPPRRLVAPS
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| BDBM50071945 |
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| n/a |
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| Name | BDBM50071945 |
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| Synonyms: | 3-[3-(1-Benzyl-piperidin-4-yl)-ureido]-benzamidine | CHEMBL327254 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H25N5O |
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| Mol. Mass. | 351.4454 |
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| SMILES | NC(=N)c1cccc(NC(=O)NC2CCN(Cc3ccccc3)CC2)c1 |
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| Structure | 
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