| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Thyrotropin-releasing hormone receptor |
|---|
| Ligand | BDBM50158395 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_1564319 |
|---|
| IC50 | 1180±n/a nM |
|---|
| Citation |  Meena, CL; Thakur, A; Nandekar, PP; Sharma, SS; Sangamwar, AT; Jain, R Synthesis and biology of ring-modified l-Histidine containing thyrotropin-releasing hormone (TRH) analogues. Eur J Med Chem111:72-83 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Thyrotropin-releasing hormone receptor |
|---|
| Name: | Thyrotropin-releasing hormone receptor |
|---|
| Synonyms: | TRH-R | TRHR_MOUSE | Thyroliberin receptor | Trhr | thyrotropin-releasing hormone R1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 44568.52 |
|---|
| Organism: | MOUSE |
|---|
| Description: | thyrotropin-releasing hormone R1 TRHR MOUSE::P21761 |
|---|
| Residue: | 393 |
|---|
| Sequence: | MENDTVSEMNQTELQPQAAVALEYQVVTILLVVIICGLGIVGNIMVVLVVMRTKHMRTPT
NCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFT
IERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKNAVVVSCG
YKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKMWKNDSIH
QNKNLNLNATNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENW
FLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKAANYSVALNYSVIKES
DRFSTELEDITVTDTYVSTTKVSFDDTCLASEN
|
|
|
|---|
| BDBM50158395 |
|---|
| n/a |
|---|
| Name | BDBM50158395 |
|---|
| Synonyms: | CHEMBL3782037 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H25IN6O4 |
|---|
| Mol. Mass. | 516.3334 |
|---|
| SMILES | CCn1cc(C[C@H](NC(=O)[C@@H]2CCC(=O)N2)C(=O)N2CCC[C@H]2C(N)=O)nc1I |r| |
|---|
| Structure | 
|
|---|
Search and Browse
