| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide FF receptor 2 |
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| Ligand | BDBM50159225 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1569167 (CHEMBL3791113) |
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| Ki | 27±n/a nM |
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| Citation |  Keller, M; Kuhn, KK; Einsiedel, J; Hübner, H; Biselli, S; Mollereau, C; Wifling, D; Svobodová, J; Bernhardt, G; Cabrele, C; Vanderheyden, PM; Gmeiner, P; Buschauer, A Mimicking of Arginine by Functionalized N(¿)-Carbamoylated Arginine As a New Broadly Applicable Approach to Labeled Bioactive Peptides: High Affinity Angiotensin, Neuropeptide Y, Neuropeptide FF, and Neurotensin Receptor Ligands As Examples. J Med Chem59:1925-45 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide FF receptor 2 |
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| Name: | Neuropeptide FF receptor 2 |
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| Synonyms: | G-protein coupled receptor 74 | G-protein coupled receptor HLWAR77 | GPR74 | NPFF2 | NPFF2_HUMAN | NPFFR2 | NPGPR | Neuropeptide FF receptor 2 | Neuropeptide G-protein coupled receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 60293.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NPFF2 0 HUMAN::Q9Y5X5 |
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| Residue: | 522 |
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| Sequence: | MNSFFGTPAASWCLLESDVSSAPDKEAGRERRALSVQQRGGPAWSGSLEWSRQSAGDRRR
LGLSRQTAKSSWSRSRDRTCCCRRAWWILVPAADRARRERFIMNEKWDTNSSENWHPIWN
VNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHT
VTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVA
IAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQN
KTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKN
QEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFA
HWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQ
LVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSSEI
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| BDBM50159225 |
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| n/a |
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| Name | BDBM50159225 |
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| Synonyms: | CHEMBL3786583 |
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| Type | Small organic molecule |
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| Emp. Form. | C76H104F9N19O23 |
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| Mol. Mass. | 1822.7381 |
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| SMILES | OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN\C(N)=N/C(=O)NCCCCN)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| |
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| Structure | 
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