| Reaction Details |
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 | Report a problem with these data |
| Target | D-amino-acid oxidase |
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| Ligand | BDBM50160750 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1566729 (CHEMBL3788101) |
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| IC50 | 30±n/a nM |
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| Citation |  Hin, N; Duvall, B; Berry, JF; Ferraris, DV; Rais, R; Alt, J; Rojas, C; Slusher, BS; Tsukamoto, T D-Amino acid oxidase inhibitors based on the 5-hydroxy-1,2,4-triazin-6(1H)-one scaffold. Bioorg Med Chem Lett26:2088-91 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D-amino-acid oxidase |
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| Name: | D-amino-acid oxidase |
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| Synonyms: | D-amino-acid oxidase (DAAO) | DAAO | DAMOX | DAO | OXDA_HUMAN |
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| Type: | Homodimer |
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| Mol. Mass.: | 39476.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14920 |
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| Residue: | 347 |
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| Sequence: | MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPN
NPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPR
ELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVN
CTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGG
IFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGP
SNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
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| BDBM50160750 |
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| n/a |
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| Name | BDBM50160750 |
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| Synonyms: | CHEMBL3786955 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H10FN3O2S |
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| Mol. Mass. | 303.312 |
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| SMILES | Oc1nc(SCc2ccc3cc(F)ccc3c2)n[nH]c1=O |
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| Structure | 
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