| Reaction Details |
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 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase |
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| Ligand | BDBM50165148 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1572749 (CHEMBL3804258) |
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| Ki | 1890±n/a nM |
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| Citation |  al-Rashida, M; Batool, G; Sattar, A; Ejaz, SA; Khan, S; Lecka, J; Sévigny, J; Hameed, A; Iqbal, J 2-Alkoxy-3-(sulfonylarylaminomethylene)-chroman-4-ones as potent and selective inhibitors of ectonucleotidases. Eur J Med Chem115:484-94 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Intestinal-type alkaline phosphatase |
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| Name: | Intestinal-type alkaline phosphatase |
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| Synonyms: | ALPI | Intestinal alkaline phosphatase | Intestinal alkaline phosphatase (IAP) | Intestinal-type alkaline phosphatase (IAP) | PPBI_BOVIN |
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| Type: | Protein |
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| Mol. Mass.: | 57094.82 |
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| Organism: | Bos taurus (Cattle) |
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| Description: | P19111 |
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| Residue: | 533 |
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| Sequence: | MQGACVLLLLGLHLQLSLGLVPVEEEDPAFWNRQAAQALDVAKKLQPIQTAAKNVILFLG
DGMGVPTVTATRILKGQMNGKLGPETPLAMDQFPYVALSKTYNVDRQVPDSAGTATAYLC
GVKGNYRTIGVSAAARYNQCKTTRGNEVTSVMNRAKKAGKSVGVVTTTRVQHASPAGAYA
HTVNRNWYSDADLPADAQMNGCQDIAAQLVNNMDIDVILGGGRKYMFPVGTPDPEYPDDA
SVNGVRKRKQNLVQAWQAKHQGAQYVWNRTALLQAADDSSVTHLMGLFEPADMKYNVQQD
HTKDPTLQEMTEVALRVVSRNPRGFYLFVEGGRIDHGHHDDKAYMALTEAGMFDNAIAKA
NELTSELDTLILVTADHSHVFSFGGYTLRGTSIFGLAPSKALDSKSYTSILYGNGPGYAL
GGGSRPDVNDSTSEDPSYQQQAAVPQASETHGGEDVAVFARGPQAHLVHGVEEETFVAHI
MAFAGCVEPYTDCNLPAPTTATSIPDAAHLAASPPPLALLAGAMLLLLAPTLY
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| BDBM50165148 |
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| n/a |
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| Name | BDBM50165148 |
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| Synonyms: | CHEMBL3797640 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H15ClN2O5S |
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| Mol. Mass. | 394.829 |
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| SMILES | COC1Oc2ccc(Cl)cc2C(=O)\C1=C/Nc1ccc(cc1)S(N)(=O)=O |
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| Structure | 
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