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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 6 | ||
| Ligand | BDBM50166857 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1572807 (CHEMBL3804531) | ||
| Ki | 129±n/a nM | ||
| Citation |  Fabritius, CH; Pesonen, U; Messinger, J; Horvath, R; Salo, H; Galezowski, M; Galek, M; Stefanska, K; Szeremeta-Spisak, J; Olszak-Plachta, M; Buda, A; Adamczyk, J; Król, M; Prusis, P; Sieprawska-Lupa, M; Mikulski, M; Kuokkanen, K; Chapman, H; Obuchowicz, R; Korjamo, T; Jalava, N; Nowak, M 1-Sulfonyl-6-Piperazinyl-7-Azaindoles as potent and pseudo-selective 5-HT6 receptor antagonists. Bioorg Med Chem Lett26:2610-5 (2016) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 5-hydroxytryptamine receptor 6 | |||
| Name: | 5-hydroxytryptamine receptor 6 | ||
| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 46968.43 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P50406 | ||
| Residue: | 440 | ||
| Sequence: |
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| BDBM50166857 | |||
| n/a | |||
| Name | BDBM50166857 | ||
| Synonyms: | CHEMBL3800055 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H29N5O3S | ||
| Mol. Mass. | 431.552 | ||
| SMILES | CC(C)CS(=O)(=O)n1ccc2c(cc(nc12)N1CCN(C)CC1)-c1c(C)noc1C |(.88,-6.25,;1.7,-5.33,;2.91,-5.58,;1.22,-3.86,;2.25,-2.71,;3.46,-2.96,;2.64,-3.88,;1.77,-1.24,;2.67,.02,;1.77,1.24,;.3,.77,;-1.03,1.56,;-2.39,.77,;-2.39,-.77,;-1.03,-1.56,;.3,-.77,;-3.73,-1.54,;-3.73,-3.09,;-5.07,-3.85,;-6.41,-3.08,;-7.48,-3.69,;-6.4,-1.53,;-5.06,-.76,;-1.03,3.1,;.22,4,;1.39,3.61,;-.27,5.46,;-1.81,5.46,;-2.28,3.99,;-3.45,3.59,)| | ||
| Structure | 
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