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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Steryl-sulfatase | ||
| Ligand | BDBM50136297 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1577311 (CHEMBL3808042) | ||
| IC50 | 970±n/a nM | ||
| Citation |  Shah, R; Singh, J; Singh, D; Jaggi, AS; Singh, N Sulfatase inhibitors for recidivist breast cancer treatment: A chemical review. Eur J Med Chem114:170-90 (2016) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Steryl-sulfatase | |||
| Name: | Steryl-sulfatase | ||
| Synonyms: | ARSC1 | ASC | Arylsulfatase C | STS | STS_HUMAN | Steroid sulfatase | Steryl-sulfate sulfohydrolase | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 65503.66 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P08842 | ||
| Residue: | 583 | ||
| Sequence: |
| ||
| BDBM50136297 | |||
| n/a | |||
| Name | BDBM50136297 | ||
| Synonyms: | CHEMBL136112 | Sulfamic acid 2-adamantan-2-ylidenemethyl-benzooxazol-6-yl ester | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H20N2O4S | ||
| Mol. Mass. | 360.427 | ||
| SMILES | NS(=O)(=O)Oc1ccc2nc(C=C3C4CC5CC(C4)CC3C5)oc2c1 |TLB:21:20:18:15.14.16,THB:21:15:12.20.19:18,16:15:12:17.19.18,16:17:12:15.14.21,11:12:18:15.14.16,(-1.25,-4.19,;.08,-3.42,;-.69,-2.08,;.85,-2.08,;1.41,-4.19,;2.76,-3.42,;2.76,-1.87,;4.09,-1.1,;5.42,-1.86,;6.91,-1.38,;7.82,-2.63,;9.36,-2.63,;10.13,-1.29,;9.45,.09,;10.55,1.03,;11.96,1.18,;12.47,2.87,;11.3,1.82,;9.8,1.7,;12.03,.4,;11.65,-1.18,;12.63,-.14,;6.91,-3.9,;5.42,-3.42,;4.09,-4.19,)| | ||
| Structure | 
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