Reaction Details |
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Target | Proteasome subunit beta type-5 |
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Ligand | BDBM50171005 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1576856 (CHEMBL3806500) |
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IC50 | >25000±n/a nM |
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Citation | McDaniel, TJ; Lansdell, TA; Dissanayake, AA; Azevedo, LM; Claes, J; Odom, AL; Tepe, JJ Substituted quinolines as noncovalent proteasome inhibitors. Bioorg Med Chem24:2441-50 (2016) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Proteasome subunit beta type-5 |
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Name: | Proteasome subunit beta type-5 |
Synonyms: | 20S proteasome chymotrypsin-like | 26S proteosome | LMPX | MB1 | PSB5_HUMAN | PSMB5 | Proteasome Macropain subunit MB1 | Proteasome subunit beta type-1/beta type-5 | X |
Type: | Protein |
Mol. Mass.: | 28480.96 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 263 |
Sequence: | MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGT
TTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLAR
QCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRI
SGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVRE
DGWIRVSSDNVADLHEKYSGSTP
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BDBM50171005 |
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n/a |
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Name | BDBM50171005 |
Synonyms: | CHEMBL3804889 |
Type | Small organic molecule |
Emp. Form. | C16H16ClN |
Mol. Mass. | 257.758 |
SMILES | Cc1nc2ccc(Cl)cc2cc1C1=CCCCC1 |t:14| |
Structure |
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