Compile Data Set for Download or QSAR

Found 52 hits with Last Name = 'azevedo' and Initial = 'lm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50069989 ((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O |r| Show InChI InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair				3D Structure (crystal)
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM32142 (5-amino-8-quinolinol | 5-aminoquinolin-8-ol | 5-az...) Show SMILES Nc1ccc(O)c2ncccc12 Show InChI InChI=1S/C9H8N2O/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate expressed in human MDAY-D2 cells assessed as free 7-ami...				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM32142 (5-amino-8-quinolinol | 5-aminoquinolin-8-ol | 5-az...) Show SMILES Nc1ccc(O)c2ncccc12 Show InChI InChI=1S/C9H8N2O/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate expressed in human K562 cells assessed as free 7-amino-...				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM32142 (5-amino-8-quinolinol | 5-aminoquinolin-8-ol | 5-az...) Show SMILES Nc1ccc(O)c2ncccc12 Show InChI InChI=1S/C9H8N2O/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate expressed in human KG1A cells assessed as free 7-amino-...				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM32142 (5-amino-8-quinolinol | 5-aminoquinolin-8-ol | 5-az...) Show SMILES Nc1ccc(O)c2ncccc12 Show InChI InChI=1S/C9H8N2O/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate expressed in human NB4 cells assessed as free 7-amino-4...				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM32142 (5-amino-8-quinolinol | 5-aminoquinolin-8-ol | 5-az...) Show SMILES Nc1ccc(O)c2ncccc12 Show InChI InChI=1S/C9H8N2O/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate expressed in human OCI-AML2 cells assessed as free 7-am...				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM32142 (5-amino-8-quinolinol | 5-aminoquinolin-8-ol | 5-az...) Show SMILES Nc1ccc(O)c2ncccc12 Show InChI InChI=1S/C9H8N2O/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate expressed in human KMS18 cells assessed as free 7-amino...				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM32142 (5-amino-8-quinolinol | 5-aminoquinolin-8-ol | 5-az...) Show SMILES Nc1ccc(O)c2ncccc12 Show InChI InChI=1S/C9H8N2O/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate expressed in human KMH11 cells assessed as free 7-amino...				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM32142 (5-amino-8-quinolinol | 5-aminoquinolin-8-ol | 5-az...) Show SMILES Nc1ccc(O)c2ncccc12 Show InChI InChI=1S/C9H8N2O/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H,10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate expressed in human UTMC2 cells assessed as free 7-amino...				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171081 (CHEMBL3805036) Show SMILES CN(C)c1ccc2nc(-c3ccccc3)c(cc2c1)-c1ccccc1 Show InChI InChI=1S/C23H20N2/c1-25(2)20-13-14-22-19(15-20)16-21(17-9-5-3-6-10-17)23(24-22)18-11-7-4-8-12-18/h3-16H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate assessed as fluorescence quinching control by fluoresce...				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50170997 (CHEMBL3805801) Show SMILES Cc1nc2ccc(cc2cc1C1=CCCCC1)N1CCCCC1 |t:13| Show InChI InChI=1S/C21H26N2/c1-16-20(17-8-4-2-5-9-17)15-18-14-19(10-11-21(18)22-16)23-12-6-3-7-13-23/h8,10-11,14-15H,2-7,9,12-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171045 (CHEMBL3805324) Show SMILES CN(C)c1ccc2ncc(cc2c1)C1CCCCC1 Show InChI InChI=1S/C17H22N2/c1-19(2)16-8-9-17-14(11-16)10-15(12-18-17)13-6-4-3-5-7-13/h8-13H,3-7H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50170999 (CHEMBL3805496) Show SMILES CCc1nc2ccc(cc2cc1C1=CCCCC1)N(C)C |t:14| Show InChI InChI=1S/C19H24N2/c1-4-18-17(14-8-6-5-7-9-14)13-15-12-16(21(2)3)10-11-19(15)20-18/h8,10-13H,4-7,9H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171000 (CHEMBL3805486) Show SMILES CN(C)c1ccc2nc(C)c(cc2c1)C1=CCCCC1 |t:16| Show InChI InChI=1S/C18H22N2/c1-13-17(14-7-5-4-6-8-14)12-15-11-16(20(2)3)9-10-18(15)19-13/h7,9-12H,4-6,8H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171001 (CHEMBL3805988) Show SMILES CN(C)c1ccc2ncc(cc2c1)C1=CCCCC1 |t:15| Show InChI InChI=1S/C17H20N2/c1-19(2)16-8-9-17-14(11-16)10-15(12-18-17)13-6-4-3-5-7-13/h6,8-12H,3-5,7H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171046 (CHEMBL3805440) Show SMILES CN(C)c1ccc2nc(C)c(cc2c1)C1CCCCC1 Show InChI InChI=1S/C18H24N2/c1-13-17(14-7-5-4-6-8-14)12-15-11-16(20(2)3)9-10-18(15)19-13/h9-12,14H,4-8H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171002 (CHEMBL3806320) Show SMILES CCCCc1ccc2nc(C)c(cc2c1)C1=CCCCC1 |t:17| Show InChI InChI=1S/C20H25N/c1-3-4-8-16-11-12-20-18(13-16)14-19(15(2)21-20)17-9-6-5-7-10-17/h9,11-14H,3-8,10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171047 (CHEMBL3805100) Show SMILES CC(C)c1ccc2nc(C)c(cc2c1)C1=CCCCC1 |t:16| Show InChI InChI=1S/C19H23N/c1-13(2)16-9-10-19-17(11-16)12-18(14(3)20-19)15-7-5-4-6-8-15/h7,9-13H,4-6,8H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171034 (CHEMBL3805013) Show SMILES Cc1cc(C)c2cc(C3CCCCC3)c(C)nc2c1 Show InChI InChI=1S/C18H23N/c1-12-9-13(2)16-11-17(14(3)19-18(16)10-12)15-7-5-4-6-8-15/h9-11,15H,4-8H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171003 (CHEMBL3805932) Show SMILES Cc1ccc2nc(C)c(cc2c1)C1=CCCCC1 |t:14| Show InChI InChI=1S/C17H19N/c1-12-8-9-17-15(10-12)11-16(13(2)18-17)14-6-4-3-5-7-14/h6,8-11H,3-5,7H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50170998 (CHEMBL3805812) Show SMILES Cc1nc2ccc(cc2cc1C1=CCCCC1)N1CCOCC1 |t:13| Show InChI InChI=1S/C20H24N2O/c1-15-19(16-5-3-2-4-6-16)14-17-13-18(7-8-20(17)21-15)22-9-11-23-12-10-22/h5,7-8,13-14H,2-4,6,9-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171006 (CHEMBL3805160) Show SMILES Cc1nc2ccc(Br)cc2cc1C1=CCCCC1 |t:14| Show InChI InChI=1S/C16H16BrN/c1-11-15(12-5-3-2-4-6-12)10-13-9-14(17)7-8-16(13)18-11/h5,7-10H,2-4,6H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171080 (CHEMBL3806316) Show SMILES CN(C)c1ccc2nc(C)c(cc2c1)-c1ccccc1 Show InChI InChI=1S/C18H18N2/c1-13-17(14-7-5-4-6-8-14)12-15-11-16(20(2)3)9-10-18(15)19-13/h4-12H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50170997 (CHEMBL3805801) Show SMILES Cc1nc2ccc(cc2cc1C1=CCCCC1)N1CCCCC1 |t:13| Show InChI InChI=1S/C21H26N2/c1-16-20(17-8-4-2-5-9-17)15-18-14-19(10-11-21(18)22-16)23-12-6-3-7-13-23/h8,10-11,14-15H,2-7,9,12-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome caspase beta1-like activity using Z-LLE-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171036 (CHEMBL3805729) Show SMILES Cc1cc(C)c2cc(cnc2c1)C1=CCCCC1 |t:14| Show InChI InChI=1S/C17H19N/c1-12-8-13(2)16-10-15(11-18-17(16)9-12)14-6-4-3-5-7-14/h6,8-11H,3-5,7H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171038 (CHEMBL3805213) Show SMILES Cc1cc(C)c2cc(C3=CCCCC3)c(C)nc2c1 |t:8| Show InChI InChI=1S/C18H21N/c1-12-9-13(2)16-11-17(14(3)19-18(16)10-12)15-7-5-4-6-8-15/h7,9-11H,4-6,8H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171039 (CHEMBL3806263) Show SMILES Cc1cc(C)c2cc(c(C)nc2c1)-c1ccccc1 Show InChI InChI=1S/C18H17N/c1-12-9-13(2)16-11-17(14(3)19-18(16)10-12)15-7-5-4-6-8-15/h4-11H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171044 (CHEMBL3805167) Show SMILES COc1cc2nc(C)c(cc2c(OC)c1OC)C1=CCCCC1 |t:19| Show InChI InChI=1S/C19H23NO3/c1-12-14(13-8-6-5-7-9-13)10-15-16(20-12)11-17(21-2)19(23-4)18(15)22-3/h8,10-11H,5-7,9H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Homo sapiens (Human))	BDBM50171038 (CHEMBL3805213) Show SMILES Cc1cc(C)c2cc(C3=CCCCC3)c(C)nc2c1 |t:8| Show InChI InChI=1S/C18H21N/c1-12-9-13(2)16-11-17(14(3)19-18(16)10-12)15-7-5-4-6-8-15/h7,9-11H,4-6,8H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome caspase beta1-like activity using Z-LLE-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171079 (CHEMBL3805403) Show SMILES CCc1cc2cc(ccc2nc1CC)N(C)C Show InChI InChI=1S/C15H20N2/c1-5-11-9-12-10-13(17(3)4)7-8-15(12)16-14(11)6-2/h7-10H,5-6H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171040 (CHEMBL3805282) Show SMILES Cc1ccc2nc(C)c(cc2c1)-c1ccccc1 Show InChI InChI=1S/C17H15N/c1-12-8-9-17-15(10-12)11-16(13(2)18-17)14-6-4-3-5-7-14/h3-11H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.92E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171037 (CHEMBL3806156) Show SMILES CCc1nc2cc(C)cc(C)c2cc1C1=CCCCC1 |t:16| Show InChI InChI=1S/C19H23N/c1-4-18-17(15-8-6-5-7-9-15)12-16-14(3)10-13(2)11-19(16)20-18/h8,10-12H,4-7,9H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171082 (CHEMBL3805379) Show SMILES CCCCc1ccc2nc(C)c(cc2c1)-c1ccccc1 Show InChI InChI=1S/C20H21N/c1-3-4-8-16-11-12-20-18(13-16)14-19(15(2)21-20)17-9-6-5-7-10-17/h5-7,9-14H,3-4,8H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171041 (CHEMBL3805307) Show SMILES Cc1cc(C)c2cc(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C17H15N/c1-12-8-13(2)16-10-15(11-18-17(16)9-12)14-6-4-3-5-7-14/h3-11H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171033 (CHEMBL3806104) Show SMILES Cc1cc(C)c2cc(-c3ccccc3)c(nc2c1)-c1ccccc1 Show InChI InChI=1S/C23H19N/c1-16-13-17(2)20-15-21(18-9-5-3-6-10-18)23(24-22(20)14-16)19-11-7-4-8-12-19/h3-15H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171005 (CHEMBL3804889) Show SMILES Cc1nc2ccc(Cl)cc2cc1C1=CCCCC1 |t:14| Show InChI InChI=1S/C16H16ClN/c1-11-15(12-5-3-2-4-6-12)10-13-9-14(17)7-8-16(13)18-11/h5,7-10H,2-4,6H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171004 (CHEMBL3805918) Show SMILES Cc1nc2ccc(F)cc2cc1C1=CCCCC1 |t:14| Show InChI InChI=1S/C16H16FN/c1-11-15(12-5-3-2-4-6-12)10-13-9-14(17)7-8-16(13)18-11/h5,7-10H,2-4,6H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171032 (CHEMBL3805787) Show SMILES Cc1nc2ccccc2cc1C1=CCCCC1 |t:13| Show InChI InChI=1S/C16H17N/c1-12-15(13-7-3-2-4-8-13)11-14-9-5-6-10-16(14)17-12/h5-7,9-11H,2-4,8H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171031 (CHEMBL3804977) Show SMILES Cc1nc2cc(Cl)cc(Cl)c2cc1C1=CCCCC1 |t:15| Show InChI InChI=1S/C16H15Cl2N/c1-10-13(11-5-3-2-4-6-11)9-14-15(18)7-12(17)8-16(14)19-10/h5,7-9H,2-4,6H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171008 (CHEMBL3805485) Show SMILES Cc1nc2cc(Br)cc(Br)c2cc1C1=CCCCC1 |t:15| Show InChI InChI=1S/C16H15Br2N/c1-10-13(11-5-3-2-4-6-11)9-14-15(18)7-12(17)8-16(14)19-10/h5,7-9H,2-4,6H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50170997 (CHEMBL3805801) Show SMILES Cc1nc2ccc(cc2cc1C1=CCCCC1)N1CCCCC1 |t:13| Show InChI InChI=1S/C21H26N2/c1-16-20(17-8-4-2-5-9-17)15-18-14-19(10-11-21(18)22-16)23-12-6-3-7-13-23/h8,10-11,14-15H,2-7,9,12-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome tryptic beta2-like activity using Z-ARR-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50171038 (CHEMBL3805213) Show SMILES Cc1cc(C)c2cc(C3=CCCCC3)c(C)nc2c1 |t:8| Show InChI InChI=1S/C18H21N/c1-12-9-13(2)16-11-17(14(3)19-18(16)10-12)15-7-5-4-6-8-15/h7,9-11H,4-6,8H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome tryptic beta2-like activity using Z-ARR-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171084 (CHEMBL3805961) Show SMILES Cc1nc2ccc(Br)cc2cc1-c1ccccc1 Show InChI InChI=1S/C16H12BrN/c1-11-15(12-5-3-2-4-6-12)10-13-9-14(17)7-8-16(13)18-11/h2-10H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171083 (CHEMBL3805152) Show SMILES CC(C)c1ccc2nc(C)c(cc2c1)-c1ccccc1 Show InChI InChI=1S/C19H19N/c1-13(2)16-9-10-19-17(11-16)12-18(14(3)20-19)15-7-5-4-6-8-15/h4-13H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171081 (CHEMBL3805036) Show SMILES CN(C)c1ccc2nc(-c3ccccc3)c(cc2c1)-c1ccccc1 Show InChI InChI=1S/C23H20N2/c1-25(2)20-13-14-22-19(15-20)16-21(17-9-5-3-6-10-17)23(24-22)18-11-7-4-8-12-18/h3-16H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171078 (CHEMBL3804847) Show SMILES CCCCc1ccc2cc(ccc2n1)N(C)C Show InChI InChI=1S/C15H20N2/c1-4-5-6-13-8-7-12-11-14(17(2)3)9-10-15(12)16-13/h7-11H,4-6H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171077 (CHEMBL3805957) Show SMILES CN(C)c1ccc2ncc(cc2c1)C(C)(C)C Show InChI InChI=1S/C15H20N2/c1-15(2,3)12-8-11-9-13(17(4)5)6-7-14(11)16-10-12/h6-10H,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171035 (CHEMBL3805830) Show SMILES CCc1nc2cc(C)cc(C)c2cc1C(C)=C Show InChI InChI=1S/C16H19N/c1-6-15-13(10(2)3)9-14-12(5)7-11(4)8-16(14)17-15/h7-9H,2,6H2,1,3-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171043 (CHEMBL3805312) Show SMILES COc1ccc2nc(C)c(cc2c1)C1=CCCCC1 |t:15| Show InChI InChI=1S/C17H19NO/c1-12-16(13-6-4-3-5-7-13)11-14-10-15(19-2)8-9-17(14)18-12/h6,8-11H,3-5,7H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50171042 (CHEMBL3805672) Show SMILES c1ccc(cc1)-c1cnc2ccccc2c1 Show InChI InChI=1S/C15H11N/c1-2-6-12(7-3-1)14-10-13-8-4-5-9-15(13)16-11-14/h1-11H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotryptic-like activity using Suc-LLVY-AMC as substrate measured for 30 mins by fluorescence assay				Bioorg Med Chem 24: 2441-50 (2016) Article DOI: 10.1016/j.bmc.2016.04.005 BindingDB Entry DOI: 10.7270/Q2PK0J26
					More data for this Ligand-Target Pair

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