| Reaction Details |
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 | Report a problem with these data |
| Target | Proteasome subunit beta type-5 |
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| Ligand | BDBM32142 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1576933 (CHEMBL3806714) |
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| IC50 | 600±n/a nM |
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| Citation |  McDaniel, TJ; Lansdell, TA; Dissanayake, AA; Azevedo, LM; Claes, J; Odom, AL; Tepe, JJ Substituted quinolines as noncovalent proteasome inhibitors. Bioorg Med Chem24:2441-50 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Proteasome subunit beta type-5 |
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| Name: | Proteasome subunit beta type-5 |
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| Synonyms: | 20S proteasome chymotrypsin-like | 26S proteosome | LMPX | MB1 | PSB5_HUMAN | PSMB5 | Proteasome Macropain subunit MB1 | Proteasome subunit beta type-1/beta type-5 | X |
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| Type: | Protein |
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| Mol. Mass.: | 28480.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 263 |
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| Sequence: | MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGT
TTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLAR
QCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRI
SGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVRE
DGWIRVSSDNVADLHEKYSGSTP
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| BDBM32142 |
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| n/a |
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| Name | BDBM32142 |
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| Synonyms: | 5-amino-8-quinolinol | 5-aminoquinolin-8-ol | 5-azanylquinolin-8-ol | AS-0308-225 | cid_416002 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H8N2O |
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| Mol. Mass. | 160.1726 |
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| SMILES | Nc1ccc(O)c2ncccc12 |
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| Structure | 
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