| Reaction Details |
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 | Report a problem with these data |
| Target | G-protein coupled receptor 4 |
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| Ligand | BDBM50175293 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1581084 (CHEMBL3813382) |
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| pH | 7.2±n/a |
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| IC50 | 910±n/a nM |
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| Comments | extracted |
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| Citation |  Fukuda, H; Ito, S; Watari, K; Mogi, C; Arisawa, M; Okajima, F; Kurose, H; Shuto, S Identification of a Potent and Selective GPR4 Antagonist as a Drug Lead for the Treatment of Myocardial Infarction. ACS Med Chem Lett7:493-7 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| G-protein coupled receptor 4 |
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| Name: | G-protein coupled receptor 4 |
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| Synonyms: | G-protein coupled receptor 4 | G-protein coupled receptor 4 (GPR4) | GPR4 | GPR4_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 40994.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P46093 |
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| Residue: | 362 |
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| Sequence: | MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLS
IADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVA
HPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAW
MNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPY
HVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKA
LHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGDQVQLKMLPP
AQ
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| BDBM50175293 |
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| n/a |
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| Name | BDBM50175293 |
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| Synonyms: | CHEMBL3808576 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H22N4S |
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| Mol. Mass. | 386.513 |
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| SMILES | CCc1nc2c(C)cc(C)nc2n1Cc1ccc2Nc3ccccc3Sc2c1 |
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| Structure | 
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