| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Shikimate kinase |
|---|
| Ligand | BDBM50182451 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1586646 (CHEMBL3822136) |
|---|
| Ki | 10900±n/a nM |
|---|
| Citation |  Prado, V; Lence, E; Maneiro, M; Vázquez-Ucha, JC; Beceiro, A; Thompson, P; Hawkins, AR; González-Bello, C Targeting the Motion of Shikimate Kinase: Development of Competitive Inhibitors that Stabilize an Inactive Open Conformation of the Enzyme. J Med Chem59:5471-87 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Shikimate kinase |
|---|
| Name: | Shikimate kinase |
|---|
| Synonyms: | AROK_HELPY | SK | aroK |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 18412.75 |
|---|
| Organism: | Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori) |
|---|
| Description: | ChEMBL_432674 |
|---|
| Residue: | 162 |
|---|
| Sequence: | MQHLVLIGFMGSGKSSLAQELGLALKLEVLDTDMIISERVGLSVREIFEELGEDNFRMFE
KNLIDELKTLKTPHVISTGGGIVMHENLKGLGTTFYLKMDFETLIKRLNQKEREKRPLLN
NLTQAKELFEKRQALYEKNASFIIDARGGLNNSLKQVLQFIA
|
|
|
|---|
| BDBM50182451 |
|---|
| n/a |
|---|
| Name | BDBM50182451 |
|---|
| Synonyms: | CHEMBL3818120 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H18O5 |
|---|
| Mol. Mass. | 278.3004 |
|---|
| SMILES | Cc1ccc(CO[C@@H]2CC(=C[C@@H](O)[C@H]2O)C(O)=O)cc1 |r,c:9| |
|---|
| Structure | 
|
|---|
Search and Browse
