| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(4) dopamine receptor |
|---|
| Ligand | BDBM50183266 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1586242 (CHEMBL3820060) |
|---|
| Ki | 0.066000±n/a nM |
|---|
| Citation |  Etukala, JR; Zhu, XY; Eyunni, SV; Onyameh, EK; Ofori, E; Bricker, BA; Kang, HJ; Huang, XP; Roth, BL; Ablordeppey, SY Development of CNS multi-receptor ligands: Modification of known D2 pharmacophores. Bioorg Med Chem24:3671-9 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(4) dopamine receptor |
|---|
| Name: | D(4) dopamine receptor |
|---|
| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 48373.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21917 |
|---|
| Residue: | 419 |
|---|
| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
|
|
|
|---|
| BDBM50183266 |
|---|
| n/a |
|---|
| Name | BDBM50183266 |
|---|
| Synonyms: | Anquil | Benperidol | Benquil | MCN-JR-4584 | R-4584 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H24FN3O2 |
|---|
| Mol. Mass. | 381.4433 |
|---|
| SMILES | Oc1nc2ccccc2n1C1CCN(CCCC(=O)c2ccc(F)cc2)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
