Found 955 hits with Last Name = 'eyunni' and Initial = 'sv' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50183266
(Anquil | Benperidol | Benquil | MCN-JR-4584 | R-45...)Show SMILES Oc1nc2ccccc2n1C1CCN(CCCC(=O)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C22H24FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-10,18H,3,6,11-15H2,(H,24,28) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 0.0270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Binding affinity to human dopamine D2 receptor by radioligand displacement assay |
Bioorg Med Chem 24: 3671-9 (2016)
Article DOI: 10.1016/j.bmc.2016.06.011 BindingDB Entry DOI: 10.7270/Q2W66NPV |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50183266
(Anquil | Benperidol | Benquil | MCN-JR-4584 | R-45...)Show SMILES Oc1nc2ccccc2n1C1CCN(CCCC(=O)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C22H24FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-10,18H,3,6,11-15H2,(H,24,28) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 0.0660 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Binding affinity to human dopamine D4 receptor by radioligand displacement assay |
Bioorg Med Chem 24: 3671-9 (2016)
Article DOI: 10.1016/j.bmc.2016.06.011 BindingDB Entry DOI: 10.7270/Q2W66NPV |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM50183266
(Anquil | Benperidol | Benquil | MCN-JR-4584 | R-45...)Show SMILES Oc1nc2ccccc2n1C1CCN(CCCC(=O)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C22H24FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-10,18H,3,6,11-15H2,(H,24,28) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 0.290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [125I]-IABN from human recombinant dopamine D3 receptor expressed in HEK293 cell membrane incubated for 60 mins filtration binding as... |
Bioorg Med Chem 24: 3671-9 (2016)
Article DOI: 10.1016/j.bmc.2016.06.011 BindingDB Entry DOI: 10.7270/Q2W66NPV |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50151982
(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)Show SMILES NC(=O)c1cc2cc(ccc2o1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 Show InChI InChI=1S/C26H27N5O2/c27-16-18-4-6-23-22(13-18)19(17-29-23)3-1-2-8-30-9-11-31(12-10-30)21-5-7-24-20(14-21)15-25(33-24)26(28)32/h4-7,13-15,17,29H,1-3,8-12H2,(H2,28,32) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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Similars
| Article PubMed
| 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting |
Eur J Med Chem 53: 124-32 (2012)
Article DOI: 10.1016/j.ejmech.2012.03.042 BindingDB Entry DOI: 10.7270/Q2PN96NS |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM21397
(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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| Article PubMed
| 0.320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Binding affinity to dopamine D3 receptor (unknown origin) |
Bioorg Med Chem 24: 3671-9 (2016)
Article DOI: 10.1016/j.bmc.2016.06.011 BindingDB Entry DOI: 10.7270/Q2W66NPV |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(RAT) | BDBM85093
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) | Reactome pathway
UniProtKB/SwissProt
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| Article PubMed
| 0.430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by PDSP assay |
Bioorg Med Chem 22: 3105-14 (2014)
Article DOI: 10.1016/j.bmc.2014.04.026 BindingDB Entry DOI: 10.7270/Q25140RW |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50151982
(5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1...)Show SMILES NC(=O)c1cc2cc(ccc2o1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 Show InChI InChI=1S/C26H27N5O2/c27-16-18-4-6-23-22(13-18)19(17-29-23)3-1-2-8-30-9-11-31(12-10-30)21-5-7-24-20(14-21)15-25(33-24)26(28)32/h4-7,13-15,17,29H,1-3,8-12H2,(H2,28,32) | PDB
KEGG
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| DrugBank PDB Article PubMed
| 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]Citalopram from human SERT by liquid scintillation counting |
Eur J Med Chem 53: 124-32 (2012)
Article DOI: 10.1016/j.ejmech.2012.03.042 BindingDB Entry DOI: 10.7270/Q2PN96NS |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
D(4) dopamine receptor
(RAT) | BDBM50384954
(CHEMBL2037521)Show InChI InChI=1S/C19H23N5S/c1-2-7-17-16(6-1)22-18(25-17)8-3-4-11-23-12-14-24(15-13-23)19-20-9-5-10-21-19/h1-2,5-7,9-10H,3-4,8,11-15H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting |
Eur J Med Chem 53: 124-32 (2012)
Article DOI: 10.1016/j.ejmech.2012.03.042 BindingDB Entry DOI: 10.7270/Q2PN96NS |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(RAT) | BDBM50384954
(CHEMBL2037521)Show InChI InChI=1S/C19H23N5S/c1-2-7-17-16(6-1)22-18(25-17)8-3-4-11-23-12-14-24(15-13-23)19-20-9-5-10-21-19/h1-2,5-7,9-10H,3-4,8,11-15H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.840 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by PDSP assay |
Bioorg Med Chem 22: 3105-14 (2014)
Article DOI: 10.1016/j.bmc.2014.04.026 BindingDB Entry DOI: 10.7270/Q25140RW |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM30130
(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)Show InChI InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3 | PDB
KEGG
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| DrugBank Article PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]Citalopram from human SERT by liquid scintillation counting |
Eur J Med Chem 53: 124-32 (2012)
Article DOI: 10.1016/j.ejmech.2012.03.042 BindingDB Entry DOI: 10.7270/Q2PN96NS |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50362863
(CHEMBL1940418)Show InChI InChI=1S/C19H24FN3/c20-18-9-7-17(8-10-18)5-2-4-12-22-13-15-23(16-14-22)19-6-1-3-11-21-19/h1,3,6-11H,2,4-5,12-16H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting |
Bioorg Med Chem 20: 1291-7 (2012)
Article DOI: 10.1016/j.bmc.2011.12.019 BindingDB Entry DOI: 10.7270/Q2Q52Q26 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50362863
(CHEMBL1940418)Show InChI InChI=1S/C19H24FN3/c20-18-9-7-17(8-10-18)5-2-4-12-22-13-15-23(16-14-22)19-6-1-3-11-21-19/h1,3,6-11H,2,4-5,12-16H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of [3H]-WAY100635 from 5HT1A receptor (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmc.2020.115943 BindingDB Entry DOI: 10.7270/Q24B34X6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM21397
(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Binding affinity to human 5HT2A receptor |
Bioorg Med Chem 24: 3671-9 (2016)
Article DOI: 10.1016/j.bmc.2016.06.011 BindingDB Entry DOI: 10.7270/Q2W66NPV |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(RAT) | BDBM50017969
(CHEMBL3289646)Show InChI InChI=1S/C19H24FN3O/c1-16-3-8-19(21-15-16)23-12-10-22(11-13-23)9-2-14-24-18-6-4-17(20)5-7-18/h3-8,15H,2,9-14H2,1H3 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by PDSP assay |
Bioorg Med Chem 22: 3105-14 (2014)
Article DOI: 10.1016/j.bmc.2014.04.026 BindingDB Entry DOI: 10.7270/Q25140RW |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50523097
(CHEMBL4533305)Show InChI InChI=1S/C20H24FN3O/c21-18-9-7-17(8-10-18)19(25)5-3-12-23-13-4-14-24(16-15-23)20-6-1-2-11-22-20/h1-2,6-11H,3-5,12-16H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of [3H]-ketanserin from human 5HT2A receptor by liquid scintillation counting |
Citation and Details
Article DOI: 10.1016/j.bmc.2020.115943 BindingDB Entry DOI: 10.7270/Q24B34X6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50183266
(Anquil | Benperidol | Benquil | MCN-JR-4584 | R-45...)Show SMILES Oc1nc2ccccc2n1C1CCN(CCCC(=O)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C22H24FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-10,18H,3,6,11-15H2,(H,24,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Binding affinity to 5HT2A receptor (unknown origin) |
Bioorg Med Chem 24: 3671-9 (2016)
Article DOI: 10.1016/j.bmc.2016.06.011 BindingDB Entry DOI: 10.7270/Q2W66NPV |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50523097
(CHEMBL4533305)Show InChI InChI=1S/C20H24FN3O/c21-18-9-7-17(8-10-18)19(25)5-3-12-23-13-4-14-24(16-15-23)20-6-1-2-11-22-20/h1-2,6-11H,3-5,12-16H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of [3H]-ketanserin from human 5HT2A receptor by liquid scintillation counting |
Citation and Details
Article DOI: 10.1016/j.bmc.2020.115943 BindingDB Entry DOI: 10.7270/Q24B34X6 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM21397
(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| Article PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Binding affinity to dopamine D4 receptor (unknown origin) |
Bioorg Med Chem 24: 3671-9 (2016)
Article DOI: 10.1016/j.bmc.2016.06.011 BindingDB Entry DOI: 10.7270/Q2W66NPV |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(RAT) | BDBM50362866
(CHEMBL1940402)Show InChI InChI=1S/C21H25ClFNO/c22-19-8-6-18(7-9-19)21(25)12-15-24(16-13-21)14-2-1-3-17-4-10-20(23)11-5-17/h4-11,25H,1-3,12-16H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting |
Bioorg Med Chem 20: 1291-7 (2012)
Article DOI: 10.1016/j.bmc.2011.12.019 BindingDB Entry DOI: 10.7270/Q2Q52Q26 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50183070
(CHEMBL3818478)Show SMILES O=C1NCN(c2ccccc2)C11CCN(CCCCc2c[nH]c3ccccc23)CC1 Show InChI InChI=1S/C25H30N4O/c30-24-25(29(19-27-24)21-9-2-1-3-10-21)13-16-28(17-14-25)15-7-6-8-20-18-26-23-12-5-4-11-22(20)23/h1-5,9-12,18,26H,6-8,13-17,19H2,(H,27,30) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from human recombinant dopamine D4 receptor incubated for 1.5 hrs by microbeta scintillation counting method |
Bioorg Med Chem 24: 3671-9 (2016)
Article DOI: 10.1016/j.bmc.2016.06.011 BindingDB Entry DOI: 10.7270/Q2W66NPV |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50183070
(CHEMBL3818478)Show SMILES O=C1NCN(c2ccccc2)C11CCN(CCCCc2c[nH]c3ccccc23)CC1 Show InChI InChI=1S/C25H30N4O/c30-24-25(29(19-27-24)21-9-2-1-3-10-21)13-16-28(17-14-25)15-7-6-8-20-18-26-23-12-5-4-11-22(20)23/h1-5,9-12,18,26H,6-8,13-17,19H2,(H,27,30) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from human recombinant dopamine D4 receptor incubated for 1.5 hrs by microbeta scintillation counting method |
Bioorg Med Chem 24: 3671-9 (2016)
Article DOI: 10.1016/j.bmc.2016.06.011 BindingDB Entry DOI: 10.7270/Q2W66NPV |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(RAT) | BDBM50362865
(CHEMBL1940420)Show InChI InChI=1S/C18H22FN3O/c19-16-5-7-17(8-6-16)23-15-3-10-21-11-13-22(14-12-21)18-4-1-2-9-20-18/h1-2,4-9H,3,10-15H2 | Reactome pathway
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting |
Bioorg Med Chem 20: 1291-7 (2012)
Article DOI: 10.1016/j.bmc.2011.12.019 BindingDB Entry DOI: 10.7270/Q2Q52Q26 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(RAT) | BDBM50362865
(CHEMBL1940420)Show InChI InChI=1S/C18H22FN3O/c19-16-5-7-17(8-6-16)23-15-3-10-21-11-13-22(14-12-21)18-4-1-2-9-20-18/h1-2,4-9H,3,10-15H2 | Reactome pathway
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
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| Article PubMed
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by PDSP assay |
Bioorg Med Chem 22: 3105-14 (2014)
Article DOI: 10.1016/j.bmc.2014.04.026 BindingDB Entry DOI: 10.7270/Q25140RW |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50001884
(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| DrugBank Article PubMed
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]pyrilamine from human H1 receptor by liquid scintillation counting |
Bioorg Med Chem 20: 1291-7 (2012)
Article DOI: 10.1016/j.bmc.2011.12.019 BindingDB Entry DOI: 10.7270/Q2Q52Q26 |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50001884
(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 | UniProtKB/SwissProt
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| Article PubMed
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]QNB from human M1 receptor by liquid scintillation counting |
Bioorg Med Chem 20: 1291-7 (2012)
Article DOI: 10.1016/j.bmc.2011.12.019 BindingDB Entry DOI: 10.7270/Q2Q52Q26 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(RAT) | BDBM50362868
(CHEMBL1940404)Show InChI InChI=1S/C20H23ClFNO2/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting |
Bioorg Med Chem 20: 1291-7 (2012)
Article DOI: 10.1016/j.bmc.2011.12.019 BindingDB Entry DOI: 10.7270/Q2Q52Q26 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(RAT) | BDBM50073805
(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyra...)Show InChI InChI=1S/C18H19ClN4/c19-16-4-6-17(7-5-16)22-11-9-21(10-12-22)14-15-13-20-23-8-2-1-3-18(15)23/h1-8,13H,9-12,14H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by PDSP assay |
Bioorg Med Chem 22: 3105-14 (2014)
Article DOI: 10.1016/j.bmc.2014.04.026 BindingDB Entry DOI: 10.7270/Q25140RW |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50130293
(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl Show InChI InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) | PDB
Reactome pathway KEGG
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| DrugBank Article PubMed
| 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of [3H]-N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting |
Citation and Details
Article DOI: 10.1016/j.bmc.2020.115943 BindingDB Entry DOI: 10.7270/Q24B34X6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50384967
(CHEMBL2037531)Show InChI InChI=1S/C23H26N2OS/c26-21(23-24-20-10-4-5-12-22(20)27-23)11-6-7-15-25-16-13-19(14-17-25)18-8-2-1-3-9-18/h1-5,8-10,12,19H,6-7,11,13-17H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation counting |
Eur J Med Chem 53: 124-32 (2012)
Article DOI: 10.1016/j.ejmech.2012.03.042 BindingDB Entry DOI: 10.7270/Q2PN96NS |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50362863
(CHEMBL1940418)Show InChI InChI=1S/C19H24FN3/c20-18-9-7-17(8-10-18)5-2-4-12-22-13-15-23(16-14-22)19-6-1-3-11-21-19/h1,3,6-11H,2,4-5,12-16H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of [3H]-methylspiperone from dopamine D4 receptor (unknown origin) |
Citation and Details
Article DOI: 10.1016/j.bmc.2020.115943 BindingDB Entry DOI: 10.7270/Q24B34X6 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(RAT) | BDBM50362863
(CHEMBL1940418)Show InChI InChI=1S/C19H24FN3/c20-18-9-7-17(8-10-18)5-2-4-12-22-13-15-23(16-14-22)19-6-1-3-11-21-19/h1,3,6-11H,2,4-5,12-16H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting |
Bioorg Med Chem 20: 1291-7 (2012)
Article DOI: 10.1016/j.bmc.2011.12.019 BindingDB Entry DOI: 10.7270/Q2Q52Q26 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(RAT) | BDBM50362863
(CHEMBL1940418)Show InChI InChI=1S/C19H24FN3/c20-18-9-7-17(8-10-18)5-2-4-12-22-13-15-23(16-14-22)19-6-1-3-11-21-19/h1,3,6-11H,2,4-5,12-16H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by PDSP assay |
Bioorg Med Chem 22: 3105-14 (2014)
Article DOI: 10.1016/j.bmc.2014.04.026 BindingDB Entry DOI: 10.7270/Q25140RW |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50384966
(CHEMBL2037530)Show InChI InChI=1S/C22H25N3OS/c26-20(22-23-19-10-4-5-12-21(19)27-22)11-6-7-13-24-14-16-25(17-15-24)18-8-2-1-3-9-18/h1-5,8-10,12H,6-7,11,13-17H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting |
Eur J Med Chem 53: 124-32 (2012)
Article DOI: 10.1016/j.ejmech.2012.03.042 BindingDB Entry DOI: 10.7270/Q2PN96NS |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50362865
(CHEMBL1940420)Show InChI InChI=1S/C18H22FN3O/c19-16-5-7-17(8-6-16)23-15-3-10-21-11-13-22(14-12-21)18-4-1-2-9-20-18/h1-2,4-9H,3,10-15H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting |
Bioorg Med Chem 20: 1291-7 (2012)
Article DOI: 10.1016/j.bmc.2011.12.019 BindingDB Entry DOI: 10.7270/Q2Q52Q26 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50384965
(CHEMBL2037529)Show InChI InChI=1S/C20H23N5OS/c26-17(19-23-16-6-1-2-8-18(16)27-19)7-3-4-11-24-12-14-25(15-13-24)20-21-9-5-10-22-20/h1-2,5-6,8-10H,3-4,7,11-15H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting |
Eur J Med Chem 53: 124-32 (2012)
Article DOI: 10.1016/j.ejmech.2012.03.042 BindingDB Entry DOI: 10.7270/Q2PN96NS |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(RAT) | BDBM50017964
(CHEMBL3289656)Show InChI InChI=1S/C18H21N5S/c1-2-6-16-15(5-1)21-17(24-16)7-3-10-22-11-13-23(14-12-22)18-19-8-4-9-20-18/h1-2,4-6,8-9H,3,7,10-14H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by PDSP assay |
Bioorg Med Chem 22: 3105-14 (2014)
Article DOI: 10.1016/j.bmc.2014.04.026 BindingDB Entry DOI: 10.7270/Q25140RW |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(RAT) | BDBM50384969
(CHEMBL2037431)Show InChI InChI=1S/C21H24ClN3S/c22-17-8-10-18(11-9-17)25-15-13-24(14-16-25)12-4-3-7-21-23-19-5-1-2-6-20(19)26-21/h1-2,5-6,8-11H,3-4,7,12-16H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting |
Eur J Med Chem 53: 124-32 (2012)
Article DOI: 10.1016/j.ejmech.2012.03.042 BindingDB Entry DOI: 10.7270/Q2PN96NS |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(RAT) | BDBM50384969
(CHEMBL2037431)Show InChI InChI=1S/C21H24ClN3S/c22-17-8-10-18(11-9-17)25-15-13-24(14-16-25)12-4-3-7-21-23-19-5-1-2-6-20(19)26-21/h1-2,5-6,8-11H,3-4,7,12-16H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by PDSP assay |
Bioorg Med Chem 22: 3105-14 (2014)
Article DOI: 10.1016/j.bmc.2014.04.026 BindingDB Entry DOI: 10.7270/Q25140RW |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM50363903
(CHEMBL1946122)Show SMILES OC1(C[C@@H]2CC[C@H](C1)N2CCCOc1ccc(F)cc1)c1ccc(Cl)cc1 |r,THB:9:8:2.1.7:5.4| Show InChI InChI=1S/C22H25ClFNO2/c23-17-4-2-16(3-5-17)22(26)14-19-8-9-20(15-22)25(19)12-1-13-27-21-10-6-18(24)7-11-21/h2-7,10-11,19-20,26H,1,8-9,12-15H2/t19-,20+,22? | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]-N-methylspiperone from dopamine D3 receptor expressed in human MES-23.5 |
Bioorg Med Chem 20: 1671-8 (2012)
Article DOI: 10.1016/j.bmc.2012.01.022 BindingDB Entry DOI: 10.7270/Q2J38T11 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(RAT) | BDBM50362862
(CHEMBL1940417)Show InChI InChI=1S/C17H21FN4O/c18-15-3-5-16(6-4-15)23-14-2-9-21-10-12-22(13-11-21)17-19-7-1-8-20-17/h1,3-8H,2,9-14H2 | Reactome pathway
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting |
Bioorg Med Chem 20: 1291-7 (2012)
Article DOI: 10.1016/j.bmc.2011.12.019 BindingDB Entry DOI: 10.7270/Q2Q52Q26 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(RAT) | BDBM50362862
(CHEMBL1940417)Show InChI InChI=1S/C17H21FN4O/c18-15-3-5-16(6-4-15)23-14-2-9-21-10-12-22(13-11-21)17-19-7-1-8-20-17/h1,3-8H,2,9-14H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by PDSP assay |
Bioorg Med Chem 22: 3105-14 (2014)
Article DOI: 10.1016/j.bmc.2014.04.026 BindingDB Entry DOI: 10.7270/Q25140RW |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(RAT) | BDBM50362859
(CHEMBL1940414)Show InChI InChI=1S/C19H24N2O/c1-3-8-18(9-4-1)21-15-13-20(14-16-21)12-7-17-22-19-10-5-2-6-11-19/h1-6,8-11H,7,12-17H2 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation counting |
Bioorg Med Chem 20: 1291-7 (2012)
Article DOI: 10.1016/j.bmc.2011.12.019 BindingDB Entry DOI: 10.7270/Q2Q52Q26 |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 | PDB
UniProtKB/SwissProt
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CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor by liquid scintillation counting |
Bioorg Med Chem 20: 1291-7 (2012)
Article DOI: 10.1016/j.bmc.2011.12.019 BindingDB Entry DOI: 10.7270/Q2Q52Q26 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50523094
(CHEMBL4462108)Show InChI InChI=1S/C19H23ClFN3/c20-17-6-9-19(22-15-17)24-13-11-23(12-14-24)10-2-1-3-16-4-7-18(21)8-5-16/h4-9,15H,1-3,10-14H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 4.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of [3H]-N-methylspiperone from human dopamine D4 receptor by liquid scintillation counting |
Citation and Details
Article DOI: 10.1016/j.bmc.2020.115943 BindingDB Entry DOI: 10.7270/Q24B34X6 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50523094
(CHEMBL4462108)Show InChI InChI=1S/C19H23ClFN3/c20-17-6-9-19(22-15-17)24-13-11-23(12-14-24)10-2-1-3-16-4-7-18(21)8-5-16/h4-9,15H,1-3,10-14H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 4.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of [3H]-N-methylspiperone from human dopamine D4 receptor by liquid scintillation counting |
Citation and Details
Article DOI: 10.1016/j.bmc.2020.115943 BindingDB Entry DOI: 10.7270/Q24B34X6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50384955
(CHEMBL2037522)Show InChI InChI=1S/C20H22N2S/c1-2-8-17-15-22(14-12-16(17)7-1)13-6-5-11-20-21-18-9-3-4-10-19(18)23-20/h1-4,7-10H,5-6,11-15H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation counting |
Eur J Med Chem 53: 124-32 (2012)
Article DOI: 10.1016/j.ejmech.2012.03.042 BindingDB Entry DOI: 10.7270/Q2PN96NS |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50523095
(CHEMBL4573441)Show InChI InChI=1S/C19H21ClFN3O/c20-16-5-8-19(22-14-16)24-12-10-23(11-13-24)9-1-2-18(25)15-3-6-17(21)7-4-15/h3-8,14H,1-2,9-13H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of [3H]-N-methylspiperone from human dopamine D4 receptor by liquid scintillation counting |
Citation and Details
Article DOI: 10.1016/j.bmc.2020.115943 BindingDB Entry DOI: 10.7270/Q24B34X6 |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM50185473
(4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....)Show SMILES OC1(CC2CCC(C1)N2CCCC(=O)c1ccc(F)cc1)c1ccc(Cl)cc1 |TLB:9:8:1.2.7:4.5,0:1:8:4.5| Show InChI InChI=1S/C23H25ClFNO2/c24-18-7-5-17(6-8-18)23(28)14-20-11-12-21(15-23)26(20)13-1-2-22(27)16-3-9-19(25)10-4-16/h3-10,20-21,28H,1-2,11-15H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Binding affinity to dopamine D3 receptor (unknown origin) |
Bioorg Med Chem 24: 3671-9 (2016)
Article DOI: 10.1016/j.bmc.2016.06.011 BindingDB Entry DOI: 10.7270/Q2W66NPV |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50523095
(CHEMBL4573441)Show InChI InChI=1S/C19H21ClFN3O/c20-16-5-8-19(22-14-16)24-12-10-23(11-13-24)9-1-2-18(25)15-3-6-17(21)7-4-15/h3-8,14H,1-2,9-13H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of [3H]-N-methylspiperone from human dopamine D4 receptor by liquid scintillation counting |
Citation and Details
Article DOI: 10.1016/j.bmc.2020.115943 BindingDB Entry DOI: 10.7270/Q24B34X6 |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50362868
(CHEMBL1940404)Show InChI InChI=1S/C20H23ClFNO2/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Florida A&M University
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation counting |
Bioorg Med Chem 20: 1291-7 (2012)
Article DOI: 10.1016/j.bmc.2011.12.019 BindingDB Entry DOI: 10.7270/Q2Q52Q26 |
More data for this Ligand-Target Pair | |