| Reaction Details |
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 | Report a problem with these data |
| Target | WD repeat-containing protein 48 |
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| Ligand | BDBM50191343 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1612851 (CHEMBL3854651) |
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| IC50 | 880±n/a nM |
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| Citation |  Korzhnev, DM; Hadden, MK Targeting the Translesion Synthesis Pathway for the Development of Anti-Cancer Chemotherapeutics. J Med Chem59:9321-9336 (2016) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| WD repeat-containing protein 48 |
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| Name: | WD repeat-containing protein 48 |
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| Synonyms: | KIAA1449 | UAF1 | USP1-associated factor 1 | Ubiquitin carboxyl-terminal hydrolase 1/WD repeat-containing protein 48 | WD repeat endosomal protein | WD repeat-containing protein 48 | WDR48 | WDR48_HUMAN | p80 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 76215.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109642 |
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| Residue: | 677 |
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| Sequence: | MAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVN
QHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYV
KALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLG
TIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLG
QQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKM
ELDRSADPPPAIWVATTKSTVNKWTLKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGG
ASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGKVDFEDEIKKRFKMVYVPNWF
SVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVN
PMDEEENEVNHVNGEQENRVQKGNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETESM
LLNETVPQWVIDITVDKNMPKFNKIPFYLQPHASSGAKTLKKDRLSASDMLQVRKVMEHV
YEKIINLDNESQTTSSSNNEKPGEQEKEEDIAVLAEEKIELLCQDQVLDPNMDLRTVKHF
IWKSGGDLTLHYRQKST
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| BDBM50191343 |
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| n/a |
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| Name | BDBM50191343 |
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| Synonyms: | CHEMBL3967184 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H10FNO3 |
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| Mol. Mass. | 295.2646 |
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| SMILES | Fc1ccc(cc1)C1=NC2C(O1)C(=O)c1ccccc1C2=O |t:8| |
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| Structure | 
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