| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
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| Ligand | BDBM50193430 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1615903 (CHEMBL3857972) |
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| Ki | 86±n/a nM |
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| Citation |  Lacivita, E; Podlewska, S; Speranza, L; Niso, M; Satala, G; Perrone, R; Perrone-Capano, C; Bojarski, AJ; Leopoldo, M Structural modifications of the serotonin 5-HT7 receptor agonist N-(4-cyanophenylmethyl)-4-(2-biphenyl)-1-piperazinehexanamide (LP-211) to improve in vitro microsomal stability: A case study. Eur J Med Chem120:363-79 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1A |
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| Name: | 5-hydroxytryptamine receptor 1A |
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| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A |
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| Type: | n/a |
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| Mol. Mass.: | 46122.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 422 |
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| Sequence: | MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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| BDBM50193430 |
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| n/a |
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| Name | BDBM50193430 |
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| Synonyms: | CHEMBL3985152 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H39N3O3 |
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| Mol. Mass. | 501.6597 |
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| SMILES | COCOc1ccc(CNC(=O)CCCCCN2CCN(CC2)c2ccccc2-c2ccccc2)cc1 |
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| Structure | 
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