Reaction Details |
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Target | Sigma non-opioid intracellular receptor 1 |
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Ligand | BDBM50193454 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1615946 (CHEMBL3858015) |
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Ki | 25±n/a nM |
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Citation | Zampieri, D; Vio, L; Fermeglia, M; Pricl, S; Wünsch, B; Schepmann, D; Romano, M; Mamolo, MG; Laurini, E Computer-assisted design, synthesis, binding and cytotoxicity assessments of new 1-(4-(aryl(methyl)amino)butyl)-heterocyclic sigma 1 ligands. Eur J Med Chem121:712-726 (2016) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Sigma non-opioid intracellular receptor 1 |
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Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
Type: | Protein |
Mol. Mass.: | 25307.17 |
Organism: | Cavia porcellus (Guinea pig) |
Description: | Q60492 |
Residue: | 223 |
Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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BDBM50193454 |
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n/a |
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Name | BDBM50193454 |
Synonyms: | CHEMBL3983612 |
Type | Small organic molecule |
Emp. Form. | C21H26N2O2 |
Mol. Mass. | 338.4433 |
SMILES | CN(CCCCN1[C@H](COC1=O)c1ccccc1)Cc1ccccc1 |r| |
Structure |
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