| Reaction Details |
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 | Report a problem with these data |
| Target | Signal transducer and activator of transcription 3 |
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| Ligand | BDBM50197961 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1620337 (CHEMBL3862620) |
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| IC50 | 38660±n/a nM |
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| Citation |  Pollastro, F; Golin, S; Chianese, G; Putra, MY; Schiano Moriello, A; De Petrocellis, L; García, V; Munoz, E; Taglialatela-Scafati, O; Appendino, G Neuroactive and Anti-inflammatory Frankincense Cembranes: A Structure-Activity Study. J Nat Prod79:1762-8 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Signal transducer and activator of transcription 3 |
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| Name: | Signal transducer and activator of transcription 3 |
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| Synonyms: | APRF | STAT3 | STAT3_HUMAN | Signal transducer and activator of transcription 3 | Signal transducer and activator of transcription 3 (STAT3) |
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| Type: | Protein |
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| Mol. Mass.: | 88064.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P40763 |
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| Residue: | 770 |
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| Sequence: | MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM
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| BDBM50197961 |
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| n/a |
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| Name | BDBM50197961 |
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| Synonyms: | CHEMBL3899770 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H50O3 |
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| Mol. Mass. | 446.7055 |
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| SMILES | CCCCCCCCC(=O)O[C@H]1CC\C(C)=C\CC\C(C)=C\C[C@@]2(CC[C@@]1(C)O2)C(C)C |r,t:15,20| |
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| Structure | 
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