Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Heat sensitive channel TRPV3 (Rattus norvegicus) | BDBM50197959 (CHEMBL3943485) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50318484 (2-((1R,6R)-6-Isopropenyl-3-methyl-cyclohex-2-enyl)...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of allylisothiocyanate-induced Ca2+ response preincubated for 5 min... | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c00668 BindingDB Entry DOI: 10.7270/Q2ZW1QJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heat sensitive channel TRPV3 (Rattus norvegicus) | BDBM50318484 (2-((1R,6R)-6-Isopropenyl-3-methyl-cyclohex-2-enyl)...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced Ca2+ response preincubated for 5 mins followed by... | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c00668 BindingDB Entry DOI: 10.7270/Q2ZW1QJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 2 (Rattus norvegicus) | BDBM50318484 (2-((1R,6R)-6-Isopropenyl-3-methyl-cyclohex-2-enyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ response preincubated for 5 mins followed by LP... | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c00668 BindingDB Entry DOI: 10.7270/Q2ZW1QJH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Heat sensitive channel TRPV3 (Rattus norvegicus) | BDBM50197965 (Incensole) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50384998 (CVD-0019905 | XANTHOHUMOL) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli MV1190 cells preincubated for 10 mins followed by addition of arachidonic acid as ... | J Nat Prod 79: 590-7 (2016) Article DOI: 10.1021/acs.jnatprod.5b01052 BindingDB Entry DOI: 10.7270/Q2639RNJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heat sensitive channel TRPV3 (Rattus norvegicus) | BDBM50197958 (CHEMBL3979367) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily M member 8 (Rattus norvegicus (Rat)) | BDBM50318484 (2-((1R,6R)-6-Isopropenyl-3-methyl-cyclohex-2-enyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced Ca2+ response preincubated for 5 mins followed by... | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c00668 BindingDB Entry DOI: 10.7270/Q2ZW1QJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50384998 (CVD-0019905 | XANTHOHUMOL) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of 5-LO in human polymorphonuclear leukocytes preincubated for 10 mins followed by addition of arachidonic acid as substrate measured afte... | J Nat Prod 79: 590-7 (2016) Article DOI: 10.1021/acs.jnatprod.5b01052 BindingDB Entry DOI: 10.7270/Q2639RNJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50318484 (2-((1R,6R)-6-Isopropenyl-3-methyl-cyclohex-2-enyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ response preincubated for 5 mins follow... | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c00668 BindingDB Entry DOI: 10.7270/Q2ZW1QJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily M member 8 (Rattus norvegicus (Rat)) | BDBM50548384 (CHEMBL4762439) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced Ca2+ response preincubated for 5 mins followed by... | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c00668 BindingDB Entry DOI: 10.7270/Q2ZW1QJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50548384 (CHEMBL4762439) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of allylisothiocyanate-induced Ca2+ response preincubated for 5 min... | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c00668 BindingDB Entry DOI: 10.7270/Q2ZW1QJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heat sensitive channel TRPV3 (Rattus norvegicus) | BDBM50197963 (CHEMBL3983336) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50177002 (CHEMBL3814590) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli MV1190 cells preincubated for 10 mins followed by addition of arachidonic acid as ... | J Nat Prod 79: 590-7 (2016) Article DOI: 10.1021/acs.jnatprod.5b01052 BindingDB Entry DOI: 10.7270/Q2639RNJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus) | BDBM50318484 (2-((1R,6R)-6-Isopropenyl-3-methyl-cyclohex-2-enyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at rat TRPV4 expressed in HEK293 cells assessed as inhibition of GSK1016790A-induced Ca2+ response preincubated for 5 mins follow... | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c00668 BindingDB Entry DOI: 10.7270/Q2ZW1QJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Homo sapiens (Human)) | BDBM50382731 (CHEMBL2023564) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Napoli Federico II Curated by ChEMBL | Assay Description Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing p4xM67-tk-Luc treated 30 mins before TNFalpha challenge measured after... | J Nat Prod 75: 453-8 (2012) Article DOI: 10.1021/np2008973 BindingDB Entry DOI: 10.7270/Q2765GB1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50177000 (CHEMBL3814665) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli MV1190 cells preincubated for 10 mins followed by addition of arachidonic acid as ... | J Nat Prod 79: 590-7 (2016) Article DOI: 10.1021/acs.jnatprod.5b01052 BindingDB Entry DOI: 10.7270/Q2639RNJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM19460 ((2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli MV1190 cells preincubated for 10 mins followed by addition of arachidonic acid as ... | J Nat Prod 79: 590-7 (2016) Article DOI: 10.1021/acs.jnatprod.5b01052 BindingDB Entry DOI: 10.7270/Q2639RNJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50177002 (CHEMBL3814590) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of 5-LO in human polymorphonuclear leukocytes preincubated for 10 mins followed by addition of arachidonic acid as substrate measured afte... | J Nat Prod 79: 590-7 (2016) Article DOI: 10.1021/acs.jnatprod.5b01052 BindingDB Entry DOI: 10.7270/Q2639RNJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50177001 (Xanthohumol C) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of 5-LO in human polymorphonuclear leukocytes preincubated for 10 mins followed by addition of arachidonic acid as substrate measured afte... | J Nat Prod 79: 590-7 (2016) Article DOI: 10.1021/acs.jnatprod.5b01052 BindingDB Entry DOI: 10.7270/Q2639RNJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM19460 ((2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of 5-LO in human polymorphonuclear leukocytes preincubated for 10 mins followed by addition of arachidonic acid as substrate measured afte... | J Nat Prod 79: 590-7 (2016) Article DOI: 10.1021/acs.jnatprod.5b01052 BindingDB Entry DOI: 10.7270/Q2639RNJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50177000 (CHEMBL3814665) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of 5-LO in human polymorphonuclear leukocytes preincubated for 10 mins followed by addition of arachidonic acid as substrate measured afte... | J Nat Prod 79: 590-7 (2016) Article DOI: 10.1021/acs.jnatprod.5b01052 BindingDB Entry DOI: 10.7270/Q2639RNJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50177003 (CHEMBL3813911) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli MV1190 cells preincubated for 10 mins followed by addition of arachidonic acid as ... | J Nat Prod 79: 590-7 (2016) Article DOI: 10.1021/acs.jnatprod.5b01052 BindingDB Entry DOI: 10.7270/Q2639RNJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50177001 (Xanthohumol C) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human 5-LO expressed in Escherichia coli MV1190 cells preincubated for 10 mins followed by addition of arachidonic acid as ... | J Nat Prod 79: 590-7 (2016) Article DOI: 10.1021/acs.jnatprod.5b01052 BindingDB Entry DOI: 10.7270/Q2639RNJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heat sensitive channel TRPV3 (Rattus norvegicus) | BDBM50548384 (CHEMBL4762439) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.18E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced Ca2+ response preincubated for 5 mins followed by... | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c00668 BindingDB Entry DOI: 10.7270/Q2ZW1QJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heat sensitive channel TRPV3 (Rattus norvegicus) | BDBM50197964 (CHEMBL3922508) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heat sensitive channel TRPV3 (Rattus norvegicus) | BDBM50197969 (CHEMBL3975348) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Homo sapiens (Human)) | BDBM50335905 ((+)-(S)-ar-turmerone | CHEMBL1668333) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.42E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of IFN gamma-induced STAT3 (unknown origin) activation in HeLa-STAT3-Luc cells after 6 hrs by luciferase reporter gene assay | J Nat Prod 79: 267-73 (2016) Article DOI: 10.1021/acs.jnatprod.5b00637 BindingDB Entry DOI: 10.7270/Q2DR2XD7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Homo sapiens (Human)) | BDBM50197965 (Incensole) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.58E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 2 (Rattus norvegicus) | BDBM50548384 (CHEMBL4762439) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ response preincubated for 5 mins followed by LP... | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c00668 BindingDB Entry DOI: 10.7270/Q2ZW1QJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50548384 (CHEMBL4762439) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ response preincubated for 5 mins follow... | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c00668 BindingDB Entry DOI: 10.7270/Q2ZW1QJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus) | BDBM50548384 (CHEMBL4762439) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at rat TRPV4 expressed in HEK293 cells assessed as inhibition of GSK1016790A-induced Ca2+ response preincubated for 5 mins follow... | Citation and Details Article DOI: 10.1021/acs.jnatprod.0c00668 BindingDB Entry DOI: 10.7270/Q2ZW1QJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heat sensitive channel TRPV3 (Rattus norvegicus) | BDBM50197970 (CHEMBL3913521) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heat sensitive channel TRPV3 (Rattus norvegicus) | BDBM50197971 (CHEMBL3890789) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heat sensitive channel TRPV3 (Rattus norvegicus) | BDBM50197961 (CHEMBL3899770) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Homo sapiens (Human)) | BDBM50197961 (CHEMBL3899770) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.87E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Homo sapiens (Human)) | BDBM50197966 (CHEMBL3959869) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Homo sapiens (Human)) | BDBM50197967 (CHEMBL3948101) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Homo sapiens (Human)) | BDBM50197968 (CHEMBL3904515) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Homo sapiens (Human)) | BDBM50197958 (CHEMBL3979367) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Homo sapiens (Human)) | BDBM50197959 (CHEMBL3943485) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Homo sapiens (Human)) | BDBM50197960 (CHEMBL3931428) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Homo sapiens (Human)) | BDBM50197962 (CHEMBL3894504) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Homo sapiens (Human)) | BDBM50197969 (CHEMBL3975348) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Homo sapiens (Human)) | BDBM50197964 (CHEMBL3922508) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Homo sapiens (Human)) | BDBM50197963 (CHEMBL3983336) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Homo sapiens (Human)) | BDBM50197970 (CHEMBL3913521) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Homo sapiens (Human)) | BDBM50197971 (CHEMBL3890789) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heat sensitive channel TRPV3 (Rattus norvegicus) | BDBM50197962 (CHEMBL3894504) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Homo sapiens (Human)) | BDBM50382730 ((-)-ALPHA-BISABOLOL | ALPHA-BISABOLOL) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Napoli Federico II Curated by ChEMBL | Assay Description Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing p4xM67-tk-Luc treated 30 mins before TNFalpha challenge measured after... | J Nat Prod 75: 453-8 (2012) Article DOI: 10.1021/np2008973 BindingDB Entry DOI: 10.7270/Q2765GB1 | |||||||||||
More data for this Ligand-Target Pair |
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