BDBM50197964 CHEMBL3922508
SMILES: CC(C)[C@@]12CC[C@@](C)(O1)[C@H](O)CC\C(C)=C\CC\C(C)=C\C2
InChI Key: InChIKey=SSBZLMMXFQMHDP-XAUKRSCVSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Heat sensitive channel TRPV3 (Rattus norvegicus) | BDBM50197964 (CHEMBL3922508) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 7.30E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Activation of rat TRPV3 overexpressed in HEK293 cells assessed as increase in 2-aminoethoxydiphenyl borate-induced intracellular calcium concentratio... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heat sensitive channel TRPV3 (Rattus norvegicus) | BDBM50197964 (CHEMBL3922508) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 3 (Homo sapiens (Human)) | BDBM50197964 (CHEMBL3922508) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ... | J Nat Prod 79: 1762-8 (2016) Article DOI: 10.1021/acs.jnatprod.6b00141 BindingDB Entry DOI: 10.7270/Q2PC34BW | |||||||||||
More data for this Ligand-Target Pair |