| Reaction Details |
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 | Report a problem with these data |
| Target | Polypeptide N-acetylgalactosaminyltransferase 2 |
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| Ligand | BDBM50200111 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1621820 (CHEMBL3864103) |
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| IC50 | 430000±n/a nM |
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| Citation |  Wang, Y; Zhu, J; Zhang, L Discovery of Cell-Permeable O-GlcNAc Transferase Inhibitors via Tethering in Situ Click Chemistry. J Med Chem60:263-272 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Polypeptide N-acetylgalactosaminyltransferase 2 |
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| Name: | Polypeptide N-acetylgalactosaminyltransferase 2 |
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| Synonyms: | GALNT2 | GALT2_HUMAN | GalNAc-T2 | Polypeptide GalNAc transferase 2 | Polypeptide N-acetylgalactosaminyltransferase 2 | Polypeptide N-acetylgalactosaminyltransferase 2 soluble form | Protein-UDP acetylgalactosaminyltransferase 2 | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2 | pp-GaNTase 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 64746.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_115316 |
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| Residue: | 571 |
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| Sequence: | MRRRSRMLLCFAFLWVLGIAYYMYSGGGSALAGGAGGGAGRKEDWNEIDPIKKKDLHHSN
GEEKAQSMETLPPGKVRWPDFNQEAYVGGTMVRSGQDPYARNKFNQVESDKLRMDRAIPD
TRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSND
PEDGALLGKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLER
VAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDYMTPEQRRSRQGNPVAP
IKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHV
FRKQHPYTFPGGSGTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQSRLELRKK
LSCKPFKWYLENVYPELRVPDHQDIAFGALQQGTNCLDTLGHFADGVVGVYECHNAGGNQ
EWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNLCL
DSRTAKSGGLSVEVCGPALSQQWKFTLNLQQ
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| BDBM50200111 |
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| n/a |
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| Name | BDBM50200111 |
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| Synonyms: | CHEMBL3981566 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H18N4O |
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| Mol. Mass. | 354.4045 |
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| SMILES | CC(=O)Nc1ccc(cc1)-n1cc(nn1)-c1ccc(cc1)-c1ccccc1 |
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| Structure | 
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