| Reaction Details |
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 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 3 |
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| Ligand | BDBM50200671 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1622750 (CHEMBL3865102) |
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| IC50 | 290±n/a nM |
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| Citation |  Bata, I; Tömösközi, Z; Buzder-Lantos, P; Vasas, A; Szeleczky, G; Bátori, S; Barta-Bodor, V; Balázs, L; Ferenczy, GG I. Discovery of a novel series of CXCR3 antagonists. Multiparametric optimization of N,N-disubstituted benzylamines. Bioorg Med Chem Lett26:5418-5428 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-X-C chemokine receptor type 3 |
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| Name: | C-X-C chemokine receptor type 3 |
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| Synonyms: | AAO92295.1 | C-X-C chemokine receptor type 3 | C-X-C chemokine receptor type 3 (CXCR3) | C-X-C chemokine receptor type 3 (CXCR3A) | CXCR3 | CXCR3A | CXCR3_HUMAN | GPR9 | chemokine (C-X-C motif) receptor 3 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40665.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 368 |
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| Sequence: | MVLEVSDHQVLNDAEVAALLENFSSSYDYGENESDSCCTSPPCPQDFSLNFDRAFLPALY
SLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADTLLVLTLPLWAVDAAVQWVFG
SGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPPARVTLTCLAVWGLCL
LFALPDFIFLSAHHDERLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILA
VLLVSRGQRRLRAMRLVVVVVVAFALCWTPYHLVVLVDILMDLGALARNCGRESRVDVAK
SVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLLLRLGCPNQRGLQRQPSSSRRDSSWSET
SEASYSGL
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| BDBM50200671 |
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| n/a |
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| Name | BDBM50200671 |
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| Synonyms: | CHEMBL3904315 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H26N2O5 |
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| Mol. Mass. | 410.4629 |
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| SMILES | COc1cc(CNCc2ccc3OCCc3c2)ccc1OCCN1C(=O)CCC1=O |
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| Structure | 
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