| Reaction Details |
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 | Report a problem with these data |
| Target | Coiled-coil domain-containing protein 6 |
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| Ligand | BDBM50203455 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1625726 (CHEMBL3868195) |
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| IC50 | 407±n/a nM |
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| Citation |  Han, M; Li, S; Ai, J; Sheng, R; Hu, Y; Hu, Y; Geng, M Discovery of 4-chloro-3-(5-(pyridin-3-yl)-1,2,4-oxadiazole-3-yl)benzamides as novel RET kinase inhibitors. Bioorg Med Chem Lett26:5679-5684 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Coiled-coil domain-containing protein 6 |
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| Name: | Coiled-coil domain-containing protein 6 |
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| Synonyms: | CCDC6 | CCDC6_HUMAN | Coiled-coil domain-containing protein 6 | D10S170 | Papillary thyroid carcinoma-encoded protein | Protein H4 | TST1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53294.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109661 |
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| Residue: | 474 |
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| Sequence: | MADSASESDTDGAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGGIVISPFRLEELT
NRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKI
QALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKK
LENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVS
APPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREE
NLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSP
SSSRPISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGTSHGITRPSPRRSNSP
DKFKRPTPPPSPNTQTPVQPPPPPPPPPMQPTVPSAATSQPTPSQHSAHPSSQP
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| BDBM50203455 |
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| n/a |
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| Name | BDBM50203455 |
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| Synonyms: | CHEMBL3906151 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H28ClF3N8O2 |
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| Mol. Mass. | 637.055 |
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| SMILES | CN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(c3)-c3noc(n3)-c3cncc(c3)-c3cnn(C)c3)cc2C(F)(F)F)CC1 |
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| Structure | 
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