Reaction Details |
| Report a problem with these data |
Target | Neurotensin receptor type 2 |
---|
Ligand | BDBM50206698 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEBML_1629221 |
---|
Ki | 110±n/a nM |
---|
Citation | Simeth, NA; Bause, M; Dobmeier, M; Kling, RC; Lachmann, D; Hübner, H; Einsiedel, J; Gmeiner, P; König, B NTS2-selective neurotensin mimetics with tetrahydrofuran amino acids. Bioorg Med Chem25:350-359 (2017) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Neurotensin receptor type 2 |
---|
Name: | Neurotensin receptor type 2 |
Synonyms: | Levocabastine-sensitive neurotensin receptor | NT-R-2 | NTR2 | NTR2 receptor | NTR2_HUMAN | NTSR2 | Neurotensin receptor | Neurotensin receptor 2 | Neurotensin receptor type 2 |
Type: | PROTEIN |
Mol. Mass.: | 45404.76 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_1281495 |
Residue: | 410 |
Sequence: | METSSPRPPRPSSNPGLSLDARLGVDTRLWAKVLFTALYALIWALGAAGNALSAHVVLKA
RAGRAGRLRHHVLSLALAGLLLLLVGVPVELYSFVWFHYPWVFGDLGCRGYYFVHELCAY
ATVLSVAGLSAERCLAVCQPLRARSLLTPRRTRWLVALSWAASLGLALPMAVIMGQKHEL
ETADGEPEPASRVCTVLVSRTALQVFIQVNVLVSFVLPLALTAFLNGVTVSHLLALCSQV
PSTSTPGSSTPSRLELLSEEGLLSFIVWKKTFIQGGQVSLVRHKDVRRIRSLQRSVQVLR
AIVVMYVICWLPYHARRLMYCYVPDDAWTDPLYNFYHYFYMVTNTLFYVSSAVTPLLYNA
VSSSFRKLFLEAVSSLCGEHHPMKRLPPKPQSPTLMDTASGFGDPPETRT
|
|
|
BDBM50206698 |
---|
n/a |
---|
Name | BDBM50206698 |
Synonyms: | CHEMBL3951982 |
Type | Small organic molecule |
Emp. Form. | C40H65BrN10O8 |
Mol. Mass. | 893.91 |
SMILES | CC[C@H](C)[C@H](NC(=O)[C@@]1(CCO[C@@H]1c1ccc(Br)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CC(C)C)C(O)=O |r| |
Structure |
|