Compile Data Set for Download or QSAR

Found 410 hits with Last Name = 'kling' and Initial = 'rc'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50436542 (CHEMBL2397389) Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@@H]1CCC(=CC1)C#C |r,c:28| Show InChI InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells				J Med Chem 56: 5130-41 (2013) Article DOI: 10.1021/jm400520c BindingDB Entry DOI: 10.7270/Q2PR7XDM
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50436541 (CHEMBL2396663) Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@H]1CCC(=CC1)C#C |r,c:28| Show InChI InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells				J Med Chem 56: 5130-41 (2013) Article DOI: 10.1021/jm400520c BindingDB Entry DOI: 10.7270/Q2PR7XDM
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50088582 (CHEMBL3577346) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2CCc3c(O)cccc3C2)nn1 |r| Show InChI InChI=1S/C34H49N5O4/c1-4-6-21-39-25-28(36-37-39)12-10-22-43-32-17-14-27(24-33(32)42-3)34(41)35-18-7-8-20-38(19-5-2)29-15-16-30-26(23-29)11-9-13-31(30)40/h9,11,13-14,17,24-25,29,40H,4-8,10,12,15-16,18-23H2,1-3H3,(H,35,41)/t29-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
Neurotensin receptor type 1 (Homo sapiens (Human))	BDBM50048908 (CHEMBL415788) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(O)=O |r| Show InChI InChI=1S/C38H64N12O8/c1-5-22(4)30(34(55)48-28(36(57)58)19-21(2)3)49-32(53)27(20-23-12-14-24(51)15-13-23)47-33(54)29-11-8-18-50(29)35(56)26(10-7-17-45-38(42)43)46-31(52)25(39)9-6-16-44-37(40)41/h12-15,21-22,25-30,51H,5-11,16-20,39H2,1-4H3,(H,46,52)(H,47,54)(H,48,55)(H,49,53)(H,57,58)(H4,40,41,44)(H4,42,43,45)/t22-,25-,26-,27-,28-,29-,30-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation counting				Bioorg Med Chem 25: 350-359 (2017) Article DOI: 10.1016/j.bmc.2016.10.039 BindingDB Entry DOI: 10.7270/Q2DR2XG4
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50436544 (CHEMBL2397479) Show SMILES CCCN(CCCCNC(=O)c1cc2ccccc2s1)[C@@H]1CCC(=CC1)C#C |r,c:25| Show InChI InChI=1S/C24H30N2OS/c1-3-16-26(21-13-11-19(4-2)12-14-21)17-8-7-15-25-24(27)23-18-20-9-5-6-10-22(20)28-23/h2,5-6,9-11,18,21H,3,7-8,12-17H2,1H3,(H,25,27)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells				J Med Chem 56: 5130-41 (2013) Article DOI: 10.1021/jm400520c BindingDB Entry DOI: 10.7270/Q2PR7XDM
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50443101 (Cariprazine | RGH-188) Show SMILES CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1 |r,wU:6.5,wD:9.9,(-.77,5.69,;.57,4.92,;1.9,5.69,;.57,3.38,;-.77,2.61,;1.9,2.61,;1.9,1.07,;3.23,.3,;3.23,-1.24,;1.9,-2.01,;1.9,-3.55,;3.23,-4.32,;3.23,-5.86,;4.57,-6.63,;4.57,-8.17,;3.23,-8.94,;1.9,-8.17,;1.9,-6.63,;3.23,-10.48,;4.57,-11.25,;4.57,-12.79,;3.23,-13.56,;1.9,-12.79,;.57,-13.56,;1.9,-11.25,;.57,-10.48,;.57,-1.24,;.57,.3,)| Show InChI InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	Article PubMed	0.270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cells by competitive binding assay				J Med Chem 57: 4861-75 (2014) Article DOI: 10.1021/jm5004039 BindingDB Entry DOI: 10.7270/Q2SN0BH5
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50119462 (CHEMBL3613880) Show SMILES Clc1cccc(N2CCN(CCCCc3cn(nn3)-c3ccn4nccc4c3)CC2)c1Cl Show InChI InChI=1S/C23H25Cl2N7/c24-21-5-3-6-22(23(21)25)30-14-12-29(13-15-30)10-2-1-4-18-17-32(28-27-18)20-8-11-31-19(16-20)7-9-26-31/h3,5-9,11,16-17H,1-2,4,10,12-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cell membranes by radioligand competition binding assay				Bioorg Med Chem 23: 6195-209 (2015) Article DOI: 10.1016/j.bmc.2015.07.050 BindingDB Entry DOI: 10.7270/Q2WW7KGM
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50018956 (CHEMBL3287405) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccn4ncc(C#N)c4c3)CC2)c1Cl Show InChI InChI=1S/C22H23Cl2N5O/c23-19-4-3-5-20(22(19)24)28-11-9-27(10-12-28)7-1-2-13-30-18-6-8-29-21(14-18)17(15-25)16-26-29/h3-6,8,14,16H,1-2,7,9-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D2 short receptor expressed in CHO cells by competitive binding assay				J Med Chem 57: 4861-75 (2014) Article DOI: 10.1021/jm5004039 BindingDB Entry DOI: 10.7270/Q2SN0BH5
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50443101 (Cariprazine | RGH-188) Show SMILES CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1 |r,wU:6.5,wD:9.9,(-.77,5.69,;.57,4.92,;1.9,5.69,;.57,3.38,;-.77,2.61,;1.9,2.61,;1.9,1.07,;3.23,.3,;3.23,-1.24,;1.9,-2.01,;1.9,-3.55,;3.23,-4.32,;3.23,-5.86,;4.57,-6.63,;4.57,-8.17,;3.23,-8.94,;1.9,-8.17,;1.9,-6.63,;3.23,-10.48,;4.57,-11.25,;4.57,-12.79,;3.23,-13.56,;1.9,-12.79,;.57,-13.56,;1.9,-11.25,;.57,-10.48,;.57,-1.24,;.57,.3,)| Show InChI InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	DrugBank Article PubMed	0.410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D2 short receptor expressed in CHO cells by competitive binding assay				J Med Chem 57: 4861-75 (2014) Article DOI: 10.1021/jm5004039 BindingDB Entry DOI: 10.7270/Q2SN0BH5
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50436543 (CHEMBL2397480) Show SMILES CCCN(CCCCNC(=O)c1cc2ccccc2s1)[C@H]1CCC(=CC1)C#C |r,c:25| Show InChI InChI=1S/C24H30N2OS/c1-3-16-26(21-13-11-19(4-2)12-14-21)17-8-7-15-25-24(27)23-18-20-9-5-6-10-22(20)28-23/h2,5-6,9-11,18,21H,3,7-8,12-17H2,1H3,(H,25,27)/t21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells				J Med Chem 56: 5130-41 (2013) Article DOI: 10.1021/jm400520c BindingDB Entry DOI: 10.7270/Q2PR7XDM
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50130293 (7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl Show InChI InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D2 short receptor expressed in CHO cells by competitive binding assay				J Med Chem 57: 4861-75 (2014) Article DOI: 10.1021/jm5004039 BindingDB Entry DOI: 10.7270/Q2SN0BH5
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50443101 (Cariprazine | RGH-188) Show SMILES CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1 |r,wU:6.5,wD:9.9,(-.77,5.69,;.57,4.92,;1.9,5.69,;.57,3.38,;-.77,2.61,;1.9,2.61,;1.9,1.07,;3.23,.3,;3.23,-1.24,;1.9,-2.01,;1.9,-3.55,;3.23,-4.32,;3.23,-5.86,;4.57,-6.63,;4.57,-8.17,;3.23,-8.94,;1.9,-8.17,;1.9,-6.63,;3.23,-10.48,;4.57,-11.25,;4.57,-12.79,;3.23,-13.56,;1.9,-12.79,;.57,-13.56,;1.9,-11.25,;.57,-10.48,;.57,-1.24,;.57,.3,)| Show InChI InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	DrugBank Article PubMed	0.470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D2 long receptor expressed in CHO cells by competitive binding assay				J Med Chem 57: 4861-75 (2014) Article DOI: 10.1021/jm5004039 BindingDB Entry DOI: 10.7270/Q2SN0BH5
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50088582 (CHEMBL3577346) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2CCc3c(O)cccc3C2)nn1 |r| Show InChI InChI=1S/C34H49N5O4/c1-4-6-21-39-25-28(36-37-39)12-10-22-43-32-17-14-27(24-33(32)42-3)34(41)35-18-7-8-20-38(19-5-2)29-15-16-30-26(23-29)11-9-13-31(30)40/h9,11,13-14,17,24-25,29,40H,4-8,10,12,15-16,18-23H2,1-3H3,(H,35,41)/t29-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2L receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50130293 (7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl Show InChI InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2L receptor expressed in CHO cell membranes by radioligand competition binding assay				Bioorg Med Chem 23: 6195-209 (2015) Article DOI: 10.1016/j.bmc.2015.07.050 BindingDB Entry DOI: 10.7270/Q2WW7KGM
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50436545 (CHEMBL2397478) Show SMILES CCCCn1ncc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2CCC(=CC2)C#C)n1 |r,c:35| Show InChI InChI=1S/C32H47N5O3/c1-5-8-22-37-34-25-28(35-37)12-11-23-40-30-18-15-27(24-31(30)39-4)32(38)33-19-9-10-21-36(20-6-2)29-16-13-26(7-3)14-17-29/h3,13,15,18,24-25,29H,5-6,8-12,14,16-17,19-23H2,1-2,4H3,(H,33,38)/t29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]7-OH-DPAT from human dopamine D2L receptor expressed in CHO cells				J Med Chem 56: 5130-41 (2013) Article DOI: 10.1021/jm400520c BindingDB Entry DOI: 10.7270/Q2PR7XDM
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50130293 (7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl Show InChI InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D2 long receptor expressed in CHO cells by competitive binding assay				J Med Chem 57: 4861-75 (2014) Article DOI: 10.1021/jm5004039 BindingDB Entry DOI: 10.7270/Q2SN0BH5
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50088582 (CHEMBL3577346) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2CCc3c(O)cccc3C2)nn1 |r| Show InChI InChI=1S/C34H49N5O4/c1-4-6-21-39-25-28(36-37-39)12-10-22-43-32-17-14-27(24-33(32)42-3)34(41)35-18-7-8-20-38(19-5-2)29-15-16-30-26(23-29)11-9-13-31(30)40/h9,11,13-14,17,24-25,29,40H,4-8,10,12,15-16,18-23H2,1-3H3,(H,35,41)/t29-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2S receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50436538 (CHEMBL2397392) Show SMILES CCCN(CCCCNC(=O)c1cnn2ccccc12)[C@@H]1CCC(=CC1)C#C |r,c:25| Show InChI InChI=1S/C23H30N4O/c1-3-15-26(20-12-10-19(4-2)11-13-20)16-8-6-14-24-23(28)21-18-25-27-17-7-5-9-22(21)27/h2,5,7,9-10,17-18,20H,3,6,8,11-16H2,1H3,(H,24,28)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]7-OH-DPAT from human dopamine D2L receptor expressed in CHO cells				J Med Chem 56: 5130-41 (2013) Article DOI: 10.1021/jm400520c BindingDB Entry DOI: 10.7270/Q2PR7XDM
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50018956 (CHEMBL3287405) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccn4ncc(C#N)c4c3)CC2)c1Cl Show InChI InChI=1S/C22H23Cl2N5O/c23-19-4-3-5-20(22(19)24)28-11-9-27(10-12-28)7-1-2-13-30-18-6-8-29-21(14-18)17(15-25)16-26-29/h3-6,8,14,16H,1-2,7,9-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D2 long receptor expressed in CHO cells by competitive binding assay				J Med Chem 57: 4861-75 (2014) Article DOI: 10.1021/jm5004039 BindingDB Entry DOI: 10.7270/Q2SN0BH5
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50119508 (CHEMBL217981) Show SMILES COc1ccccc1N1CCN(CCCCCNC(=O)c2nnn(Cc3ccccc3Br)c2C)CC1 Show InChI InChI=1S/C27H35BrN6O2/c1-21-26(30-31-34(21)20-22-10-4-5-11-23(22)28)27(35)29-14-8-3-9-15-32-16-18-33(19-17-32)24-12-6-7-13-25(24)36-2/h4-7,10-13H,3,8-9,14-20H2,1-2H3,(H,29,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2L receptor expressed in CHO cell membranes by radioligand competition binding assay				Bioorg Med Chem 23: 6195-209 (2015) Article DOI: 10.1016/j.bmc.2015.07.050 BindingDB Entry DOI: 10.7270/Q2WW7KGM
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50436542 (CHEMBL2397389) Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@@H]1CCC(=CC1)C#C |r,c:28| Show InChI InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]7-OH-DPAT from human dopamine D2L receptor expressed in CHO cells				J Med Chem 56: 5130-41 (2013) Article DOI: 10.1021/jm400520c BindingDB Entry DOI: 10.7270/Q2PR7XDM
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50436542 (CHEMBL2397389) Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@@H]1CCC(=CC1)C#C |r,c:28| Show InChI InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]7-OH-DPAT from human dopamine D2L receptor expressed in CHO cells				J Med Chem 56: 5130-41 (2013) Article DOI: 10.1021/jm400520c BindingDB Entry DOI: 10.7270/Q2PR7XDM
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50088578 (CHEMBL3577342) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2COC(=CC2)C#C)nn1 |r,c:34| Show InChI InChI=1S/C31H45N5O4/c1-5-8-20-36-23-26(33-34-36)12-11-21-39-29-16-13-25(22-30(29)38-4)31(37)32-17-9-10-19-35(18-6-2)27-14-15-28(7-3)40-24-27/h3,13,15-16,22-23,27H,5-6,8-12,14,17-21,24H2,1-2,4H3,(H,32,37)/t27-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50119462 (CHEMBL3613880) Show SMILES Clc1cccc(N2CCN(CCCCc3cn(nn3)-c3ccn4nccc4c3)CC2)c1Cl Show InChI InChI=1S/C23H25Cl2N7/c24-21-5-3-6-22(23(21)25)30-14-12-29(13-15-30)10-2-1-4-18-17-32(28-27-18)20-8-11-31-19(16-20)7-9-26-31/h3,5-9,11,16-17H,1-2,4,10,12-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor expressed in HEK293 cell membranes by radioligand competition binding assay				Bioorg Med Chem 23: 6195-209 (2015) Article DOI: 10.1016/j.bmc.2015.07.050 BindingDB Entry DOI: 10.7270/Q2WW7KGM
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50018955 (CHEMBL3287404) Show SMILES O\N=C\c1cc2cc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)ccn2n1 Show InChI InChI=1S/C22H25Cl2N5O2/c23-20-4-3-5-21(22(20)24)28-11-9-27(10-12-28)7-1-2-13-31-19-6-8-29-18(15-19)14-17(26-29)16-25-30/h3-6,8,14-16,30H,1-2,7,9-13H2/b25-16+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	0.860	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cells by competitive binding assay				J Med Chem 57: 4861-75 (2014) Article DOI: 10.1021/jm5004039 BindingDB Entry DOI: 10.7270/Q2SN0BH5
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50119510 (CHEMBL221129) Show SMILES CCCc1c(nnn1Cc1ccccc1Br)C(=O)NCCCCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C29H39BrN6O2/c1-3-11-26-28(32-33-36(26)22-23-12-5-6-13-24(23)30)29(37)31-16-9-4-10-17-34-18-20-35(21-19-34)25-14-7-8-15-27(25)38-2/h5-8,12-15H,3-4,9-11,16-22H2,1-2H3,(H,31,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2L receptor expressed in CHO cell membranes by radioligand competition binding assay				Bioorg Med Chem 23: 6195-209 (2015) Article DOI: 10.1016/j.bmc.2015.07.050 BindingDB Entry DOI: 10.7270/Q2WW7KGM
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50436541 (CHEMBL2396663) Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@H]1CCC(=CC1)C#C |r,c:28| Show InChI InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50436545 (CHEMBL2397478) Show SMILES CCCCn1ncc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2CCC(=CC2)C#C)n1 |r,c:35| Show InChI InChI=1S/C32H47N5O3/c1-5-8-22-37-34-25-28(35-37)12-11-23-40-30-18-15-27(24-31(30)39-4)32(38)33-19-9-10-21-36(20-6-2)29-16-13-26(7-3)14-17-29/h3,13,15,18,24-25,29H,5-6,8-12,14,16-17,19-23H2,1-2,4H3,(H,33,38)/t29-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells				J Med Chem 56: 5130-41 (2013) Article DOI: 10.1021/jm400520c BindingDB Entry DOI: 10.7270/Q2PR7XDM
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50436537 (CHEMBL2397476) Show SMILES CCCN(CCCCNC(=O)c1cnn2ccccc12)[C@H]1CCC(=CC1)C#C |r,c:25| Show InChI InChI=1S/C23H30N4O/c1-3-15-26(20-12-10-19(4-2)11-13-20)16-8-6-14-24-23(28)21-18-25-27-17-7-5-9-22(21)27/h2,5,7,9-10,17-18,20H,3,6,8,11-16H2,1H3,(H,24,28)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]7-OH-DPAT from human dopamine D2L receptor expressed in CHO cells				J Med Chem 56: 5130-41 (2013) Article DOI: 10.1021/jm400520c BindingDB Entry DOI: 10.7270/Q2PR7XDM
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50436541 (CHEMBL2396663) Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@H]1CCC(=CC1)C#C |r,c:28| Show InChI InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]7-OH-DPAT from human dopamine D2L receptor expressed in CHO cells				J Med Chem 56: 5130-41 (2013) Article DOI: 10.1021/jm400520c BindingDB Entry DOI: 10.7270/Q2PR7XDM
					More data for this Ligand-Target Pair
Neurotensin receptor type 2 (Homo sapiens (Human))	BDBM50048908 (CHEMBL415788) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(O)=O |r| Show InChI InChI=1S/C38H64N12O8/c1-5-22(4)30(34(55)48-28(36(57)58)19-21(2)3)49-32(53)27(20-23-12-14-24(51)15-13-23)47-33(54)29-11-8-18-50(29)35(56)26(10-7-17-45-38(42)43)46-31(52)25(39)9-6-16-44-37(40)41/h12-15,21-22,25-30,51H,5-11,16-20,39H2,1-4H3,(H,46,52)(H,47,54)(H,48,55)(H,49,53)(H,57,58)(H4,40,41,44)(H4,42,43,45)/t22-,25-,26-,27-,28-,29-,30-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation counting				Bioorg Med Chem 25: 350-359 (2017) Article DOI: 10.1016/j.bmc.2016.10.039 BindingDB Entry DOI: 10.7270/Q2DR2XG4
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50088581 (CHEMBL3577345) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@@H]2CCc3c(O)cccc3C2)nn1 |r| Show InChI InChI=1S/C34H49N5O4/c1-4-6-21-39-25-28(36-37-39)12-10-22-43-32-17-14-27(24-33(32)42-3)34(41)35-18-7-8-20-38(19-5-2)29-15-16-30-26(23-29)11-9-13-31(30)40/h9,11,13-14,17,24-25,29,40H,4-8,10,12,15-16,18-23H2,1-3H3,(H,35,41)/t29-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50018947 (CHEMBL3287396) Show SMILES OCc1cc2cc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)ccn2n1 Show InChI InChI=1S/C22H26Cl2N4O2/c23-20-4-3-5-21(22(20)24)27-11-9-26(10-12-27)7-1-2-13-30-19-6-8-28-18(15-19)14-17(16-29)25-28/h3-6,8,14-15,29H,1-2,7,9-13,16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cells by competitive binding assay				J Med Chem 57: 4861-75 (2014) Article DOI: 10.1021/jm5004039 BindingDB Entry DOI: 10.7270/Q2SN0BH5
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50018956 (CHEMBL3287405) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccn4ncc(C#N)c4c3)CC2)c1Cl Show InChI InChI=1S/C22H23Cl2N5O/c23-19-4-3-5-20(22(19)24)28-11-9-27(10-12-28)7-1-2-13-30-18-6-8-29-21(14-18)17(15-25)16-26-29/h3-6,8,14,16H,1-2,7,9-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cells by competitive binding assay				J Med Chem 57: 4861-75 (2014) Article DOI: 10.1021/jm5004039 BindingDB Entry DOI: 10.7270/Q2SN0BH5
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50119515 (CHEMBL221866) Show SMILES COc1ccc(Cn2nnc(C(=O)NCCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)c2C)cc1 Show InChI InChI=1S/C27H34Cl2N6O2/c1-20-26(31-32-35(20)19-21-9-11-22(37-2)12-10-21)27(36)30-13-4-3-5-14-33-15-17-34(18-16-33)24-8-6-7-23(28)25(24)29/h6-12H,3-5,13-19H2,1-2H3,(H,30,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2L receptor expressed in CHO cell membranes by radioligand competition binding assay				Bioorg Med Chem 23: 6195-209 (2015) Article DOI: 10.1016/j.bmc.2015.07.050 BindingDB Entry DOI: 10.7270/Q2WW7KGM
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50088578 (CHEMBL3577342) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2COC(=CC2)C#C)nn1 |r,c:34| Show InChI InChI=1S/C31H45N5O4/c1-5-8-20-36-23-26(33-34-36)12-11-21-39-29-16-13-25(22-30(29)38-4)31(37)32-17-9-10-19-35(18-6-2)27-14-15-28(7-3)40-24-27/h3,13,15-16,22-23,27H,5-6,8-12,14,17-21,24H2,1-2,4H3,(H,32,37)/t27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2L receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50088580 (CHEMBL3577344) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)CCc2ccc(O)c3[nH]c(=O)ccc23)nn1 Show InChI InChI=1S/C35H48N6O5/c1-4-6-21-41-25-28(38-39-41)10-9-23-46-31-15-12-27(24-32(31)45-3)35(44)36-18-7-8-20-40(19-5-2)22-17-26-11-14-30(42)34-29(26)13-16-33(43)37-34/h11-16,24-25,42H,4-10,17-23H2,1-3H3,(H,36,44)(H,37,43)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50018954 (CHEMBL3287403) Show SMILES O\N=C\c1cnn2ccc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)cc12 Show InChI InChI=1S/C22H25Cl2N5O2/c23-19-4-3-5-20(22(19)24)28-11-9-27(10-12-28)7-1-2-13-31-18-6-8-29-21(14-18)17(15-25-29)16-26-30/h3-6,8,14-16,30H,1-2,7,9-13H2/b26-16+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D2 short receptor expressed in CHO cells by competitive binding assay				J Med Chem 57: 4861-75 (2014) Article DOI: 10.1021/jm5004039 BindingDB Entry DOI: 10.7270/Q2SN0BH5
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50018954 (CHEMBL3287403) Show SMILES O\N=C\c1cnn2ccc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)cc12 Show InChI InChI=1S/C22H25Cl2N5O2/c23-19-4-3-5-20(22(19)24)28-11-9-27(10-12-28)7-1-2-13-31-18-6-8-29-21(14-18)17(15-25-29)16-26-30/h3-6,8,14-16,30H,1-2,7,9-13H2/b26-16+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D2 long receptor expressed in CHO cells by competitive binding assay				J Med Chem 57: 4861-75 (2014) Article DOI: 10.1021/jm5004039 BindingDB Entry DOI: 10.7270/Q2SN0BH5
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50018957 (CHEMBL3287406) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccn4nc(cc4c3)C#N)CC2)c1Cl Show InChI InChI=1S/C22H23Cl2N5O/c23-20-4-3-5-21(22(20)24)28-11-9-27(10-12-28)7-1-2-13-30-19-6-8-29-18(15-19)14-17(16-25)26-29/h3-6,8,14-15H,1-2,7,9-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cells by competitive binding assay				J Med Chem 57: 4861-75 (2014) Article DOI: 10.1021/jm5004039 BindingDB Entry DOI: 10.7270/Q2SN0BH5
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50436543 (CHEMBL2397480) Show SMILES CCCN(CCCCNC(=O)c1cc2ccccc2s1)[C@H]1CCC(=CC1)C#C |r,c:25| Show InChI InChI=1S/C24H30N2OS/c1-3-16-26(21-13-11-19(4-2)12-14-21)17-8-7-15-25-24(27)23-18-20-9-5-6-10-22(20)28-23/h2,5-6,9-11,18,21H,3,7-8,12-17H2,1H3,(H,25,27)/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]7-OH-DPAT from human dopamine D2L receptor expressed in CHO cells				J Med Chem 56: 5130-41 (2013) Article DOI: 10.1021/jm400520c BindingDB Entry DOI: 10.7270/Q2PR7XDM
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50436543 (CHEMBL2397480) Show SMILES CCCN(CCCCNC(=O)c1cc2ccccc2s1)[C@H]1CCC(=CC1)C#C |r,c:25| Show InChI InChI=1S/C24H30N2OS/c1-3-16-26(21-13-11-19(4-2)12-14-21)17-8-7-15-25-24(27)23-18-20-9-5-6-10-22(20)28-23/h2,5-6,9-11,18,21H,3,7-8,12-17H2,1H3,(H,25,27)/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]7-OH-DPAT from human dopamine D2L receptor expressed in CHO cells				J Med Chem 56: 5130-41 (2013) Article DOI: 10.1021/jm400520c BindingDB Entry DOI: 10.7270/Q2PR7XDM
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50018950 (CHEMBL3287399) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4c(C=O)cnn4c3)CC2)c1Cl Show InChI InChI=1S/C22H24Cl2N4O2/c23-19-4-3-5-21(22(19)24)27-11-9-26(10-12-27)8-1-2-13-30-18-6-7-20-17(16-29)14-25-28(20)15-18/h3-7,14-16H,1-2,8-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cells by competitive binding assay				J Med Chem 57: 4861-75 (2014) Article DOI: 10.1021/jm5004039 BindingDB Entry DOI: 10.7270/Q2SN0BH5
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50018946 (CHEMBL3287395) Show SMILES CCOC(=O)c1cc2cc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)ccn2n1 Show InChI InChI=1S/C24H28Cl2N4O3/c1-2-32-24(31)21-17-18-16-19(8-10-30(18)27-21)33-15-4-3-9-28-11-13-29(14-12-28)22-7-5-6-20(25)23(22)26/h5-8,10,16-17H,2-4,9,11-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cells by competitive binding assay				J Med Chem 57: 4861-75 (2014) Article DOI: 10.1021/jm5004039 BindingDB Entry DOI: 10.7270/Q2SN0BH5
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50018943 (CHEMBL3287392) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4ccnn4c3)CC2)c1Cl Show InChI InChI=1S/C21H24Cl2N4O/c22-19-4-3-5-20(21(19)23)26-13-11-25(12-14-26)10-1-2-15-28-18-7-6-17-8-9-24-27(17)16-18/h3-9,16H,1-2,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D2 short receptor expressed in CHO cells by competitive binding assay				J Med Chem 57: 4861-75 (2014) Article DOI: 10.1021/jm5004039 BindingDB Entry DOI: 10.7270/Q2SN0BH5
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50119457 (CHEMBL3613878) Show SMILES Clc1cccc(N2CCN(CCc3cn(nn3)-c3ccn4nccc4c3)CC2)c1Cl Show InChI InChI=1S/C21H21Cl2N7/c22-19-2-1-3-20(21(19)23)28-12-10-27(11-13-28)8-5-16-15-30(26-25-16)18-6-9-29-17(14-18)4-7-24-29/h1-4,6-7,9,14-15H,5,8,10-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cell membranes by radioligand competition binding assay				Bioorg Med Chem 23: 6195-209 (2015) Article DOI: 10.1016/j.bmc.2015.07.050 BindingDB Entry DOI: 10.7270/Q2WW7KGM
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50088579 (CHEMBL3577343) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@@H]2COC(=CC2)C#C)nn1 |r,c:34| Show InChI InChI=1S/C31H45N5O4/c1-5-8-20-36-23-26(33-34-36)12-11-21-39-29-16-13-25(22-30(29)38-4)31(37)32-17-9-10-19-35(18-6-2)27-14-15-28(7-3)40-24-27/h3,13,15-16,22-23,27H,5-6,8-12,14,17-21,24H2,1-2,4H3,(H,32,37)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50018954 (CHEMBL3287403) Show SMILES O\N=C\c1cnn2ccc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)cc12 Show InChI InChI=1S/C22H25Cl2N5O2/c23-19-4-3-5-20(22(19)24)28-11-9-27(10-12-28)7-1-2-13-31-18-6-8-29-21(14-18)17(15-25-29)16-26-30/h3-6,8,14-16,30H,1-2,7,9-13H2/b26-16+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cells by competitive binding assay				J Med Chem 57: 4861-75 (2014) Article DOI: 10.1021/jm5004039 BindingDB Entry DOI: 10.7270/Q2SN0BH5
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50018943 (CHEMBL3287392) Show SMILES Clc1cccc(N2CCN(CCCCOc3ccc4ccnn4c3)CC2)c1Cl Show InChI InChI=1S/C21H24Cl2N4O/c22-19-4-3-5-20(21(19)23)26-13-11-25(12-14-26)10-1-2-15-28-18-7-6-17-8-9-24-27(17)16-18/h3-9,16H,1-2,10-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cells by competitive binding assay				J Med Chem 57: 4861-75 (2014) Article DOI: 10.1021/jm5004039 BindingDB Entry DOI: 10.7270/Q2SN0BH5
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50018955 (CHEMBL3287404) Show SMILES O\N=C\c1cc2cc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)ccn2n1 Show InChI InChI=1S/C22H25Cl2N5O2/c23-20-4-3-5-21(22(20)24)28-11-9-27(10-12-28)7-1-2-13-31-19-6-8-29-18(15-19)14-17(26-29)16-25-30/h3-6,8,14-16,30H,1-2,7,9-13H2/b25-16+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human dopamine D2 short receptor expressed in CHO cells by competitive binding assay				J Med Chem 57: 4861-75 (2014) Article DOI: 10.1021/jm5004039 BindingDB Entry DOI: 10.7270/Q2SN0BH5
					More data for this Ligand-Target Pair

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