| Reaction Details |
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 | Report a problem with these data |
| Target | Glucose-dependent insulinotropic receptor |
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| Ligand | BDBM50207292 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1630588 (CHEMBL3873294) |
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| EC50 | 1900±n/a nM |
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| Citation |  Li, G; Huan, Y; Yuan, B; Wang, J; Jiang, Q; Lin, Z; Shen, Z; Huang, H Discovery of novel xanthine compounds targeting DPP-IV and GPR119 as anti-diabetic agents. Eur J Med Chem124:103-116 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucose-dependent insulinotropic receptor |
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| Name: | Glucose-dependent insulinotropic receptor |
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| Synonyms: | G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor |
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| Type: | Protein |
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| Mol. Mass.: | 36901.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8TDV5 |
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| Residue: | 335 |
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| Sequence: | MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISG
LLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGF
VAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLL
FVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTP
FLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKV
LTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
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| BDBM50207292 |
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| n/a |
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| Name | BDBM50207292 |
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| Synonyms: | CHEMBL3911786 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H37N7O4 |
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| Mol. Mass. | 499.6058 |
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| SMILES | CC#CCn1c(nc2n(C)c(=O)n(CC3CCN(CC3)C(=O)OC(C)C)c(=O)c12)N1CCC[C@@H](N)C1 |r| |
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| Structure | 
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