| Reaction Details |
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 | Report a problem with these data |
| Target | Sporulation kinase A |
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| Ligand | BDBM50215974 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_92720 (CHEMBL872510) |
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| IC50 | 37000±n/a nM |
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| Citation |  Sui, Z; Guan, J; Hlasta, DJ; Macielag, MJ; Foleno, BD; Goldschmidt, RM; Loeloff, MJ; Webb, GC; Barrett, JF SAR studies of diaryltriazoles against bacterial two-component regulatory systems and their antibacterial activities. Bioorg Med Chem Lett8:1929-34 (1998) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sporulation kinase A |
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| Name: | Sporulation kinase A |
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| Synonyms: | KINA_BACSU | Sporulation kinase A | Stage II sporulation protein F | Stage II sporulation protein J | gsiC | kinA | scoD | spoIIF | spoIIJ |
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| Type: | PROTEIN |
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| Mol. Mass.: | 69161.05 |
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| Organism: | Bacillus subtilis (strain 168) |
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| Description: | ChEMBL_105028 |
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| Residue: | 606 |
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| Sequence: | MEQDTQHVKPLQTKTDIHAVLASNGRIIYISANSKLHLGYLQGEMIGSFLKTFLHEEDQF
LVESYFYNEHHLMPCTFRFIKKDHTIVWVEAAVEIVTTRAERTEREIILKMKVLEEETGH
QSLNCEKHEIEPASPESTTYITDDYERLVENLPSPLCISVKGKIVYVNSAMLSMLGAKSK
DAIIGKSSYEFIEEEYHDIVKNRIIRMQKGMEVGMIEQTWKRLDGTPVHLEVKASPTVYK
NQQAELLLLIDISSRKKFQTILQKSRERYQLLIQNSIDTIAVIHNGKWVFMNESGISLFE
AATYEDLIGKNIYDQLHPCDHEDVKERIQNIAEQKTESEIVKQSWFTFQNRVIYTEMVCI
PTTFFGEAAVQVILRDISERKQTEELMLKSEKLSIAGQLAAGIAHEIRNPLTAIKGFLQL
MKPTMEGNEHYFDIVFSELSRIELILSELLMLAKPQQNAVKEYLNLKKLIGEVSALLETQ
ANLNGIFIRTSYEKDSIYINGDQNQLKQVFINLIKNAVESMPDGGTVDIIITEDEHSVHV
TVKDEGEGIPEKVLNRIGEPFLTTKEKGTGLGLMVTFNIIENHQGVIHVDSHPEKGTAFK
ISFPKK
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| BDBM50215974 |
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| n/a |
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| Name | BDBM50215974 |
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| Synonyms: | 3,3'',4'',5-tetrachlorosalicylanilide | 3,3',4',5-TETRACHLOROSALICYLANILIDE | CHEBI:188648 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H7Cl4NO2 |
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| Mol. Mass. | 351.012 |
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| SMILES | Oc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(Cl)c(Cl)c1 |
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| Structure | 
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