| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50216348 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_60532 (CHEMBL674943) |
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| Ki | 501±n/a nM |
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| Citation |  Avenell, KY; Boyfield, I; Coldwell, MC; Hadley, MS; Healy, MA; Jeffrey, PM; Johnson, CN; Nash, DJ; Riley, GJ; Scott, EE; Smith, SA; Stacey, R; Stemp, G; Thewlis, KM Fused aminotetralins: novel antagonists with high selectivity for the dopamine D3 receptor. Bioorg Med Chem Lett8:2859-64 (1998) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50216348 |
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| n/a |
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| Name | BDBM50216348 |
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| Synonyms: | CHEMBL95759 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H34N2O2 |
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| Mol. Mass. | 454.6032 |
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| SMILES | [H][C@]12CCc3cc(O)ccc3[C@]1([H])CCCN2CCCCNC(=O)c1ccc(cc1)-c1ccccc1 |
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| Structure | 
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