| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50215536 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_83628 (CHEMBL858407) |
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| Ki | 0.151356±n/a nM |
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| Citation |  Tozer, MJ; Harper, EA; Kalindjian, SB; Pether, MJ; Shankley, NP; Watt, GF From histamine to imidazolylalkyl-sulfonamides: the design of a novel series of histamine H3-receptor antagonists. Bioorg Med Chem Lett9:1825-30 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HISTAMINE H3 | HRH3 | HRH3_CAVPO | Histamine H3 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 48753.61 |
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| Organism: | GUINEA PIG |
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| Description: | HISTAMINE H3 HRH3 GUINEA PIG::Q9JI35 |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGALAGEAAAAAGGARTFSAAWTAVLAALMALLIVATVLGNALVMLAF
VADSSLRTQNNFFLLNLAISDFLVGVFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCT
SSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMVLVWVLAFLLYGPAILSWEYLSG
GSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGARE
AGPDPLPEAQSSPPQPPPGCWGCWPKGQGESMPLHRYGVGEAGPGAEAGEAALGGGSGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHSSLEHCWK
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| BDBM50215536 |
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| n/a |
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| Name | BDBM50215536 |
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| Synonyms: | (R)-Alpha-Methylhistamine | CHEBI:73337 | CHEMBL268229 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H11N3 |
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| Mol. Mass. | 125.1716 |
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| SMILES | C[C@@H](N)Cc1c[nH]cn1 |r| |
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| Structure | 
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