Reaction Details |
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Target | Similar to alpha-tubulin isoform 1 |
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Ligand | BDBM50212289 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_211321 (CHEMBL818980) |
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IC50 | 7700±n/a nM |
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Citation | Getahun, Z; Jurd, L; Chu, PS; Lin, CM; Hamel, E Synthesis of alkoxy-substituted diaryl compounds and correlation of ring separation with inhibition of tubulin polymerization: differential enhancement of inhibitory effects under suboptimal polymerization reaction conditions. J Med Chem35:1058-67 (1992) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Similar to alpha-tubulin isoform 1 |
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Name: | Similar to alpha-tubulin isoform 1 |
Synonyms: | Similar to alpha-tubulin isoform 1 |
Type: | PROTEIN |
Mol. Mass.: | 10383.05 |
Organism: | Bos taurus |
Description: | ChEMBL_104716 |
Residue: | 99 |
Sequence: | CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
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BDBM50212289 |
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n/a |
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Name | BDBM50212289 |
Synonyms: | CHEMBL10121 |
Type | Small organic molecule |
Emp. Form. | C17H20O5 |
Mol. Mass. | 304.3377 |
SMILES | COc1ccc(Cc2cc(OC)c(OC)c(OC)c2)cc1O |
Structure |
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