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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Lactoylglutathione lyase | ||
| Ligand | BDBM50045936 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1648196 (CHEMBL3997252) | ||
| IC50 | 760±n/a nM | ||
| Citation |  Takasawa, R; Akahane, H; Tanaka, H; Shimada, N; Yamamoto, T; Uchida-Maruki, H; Sai, M; Yoshimori, A; Tanuma, SI Piceatannol, a natural trans-stilbene compound, inhibits human glyoxalase I. Bioorg Med Chem Lett27:1169-1174 (2017) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Lactoylglutathione lyase | |||
| Name: | Lactoylglutathione lyase | ||
| Synonyms: | Aldoketomutase | GLO1 | Glx I | Glyoxalase 1 (GLO1) | Glyoxalase I | Ketone-aldehyde mutase | LGUL_HUMAN | Methylglyoxalase | S-D-lactoylglutathione methylglyoxal lyase | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 20772.95 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q04760 | ||
| Residue: | 184 | ||
| Sequence: |
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| BDBM50045936 | |||
| n/a | |||
| Name | BDBM50045936 | ||
| Synonyms: | (E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol | (E)-Piceatannol | 3,3',4,5'-tetrahydroxystilbene | 3,4,3',5'-tetrahydroxy-trans-stilbene | 3,4,3',5'-tetrahydroxystillbene | 4-(3,5-dihydroxystyryl)benzene-1,2-diol | 4-[(E)-2-(3,5-dihydroxyphenyl)vinyl]benzene-1,2-diol | 4-[(E)-2-(3,5-dihydroxyphenyl)vinyl]benzene-1,2-diol(Piceatannol) | 4-[2-(3,5-dihydroxyphenyl)-(E)-1-ethenyl]-1,2-benzenediol | 4-[2-(3,5-dihydroxyphenyl)-(E)-1-ethenyl]-1,2-benzenediol(Piceatannol) | CHEMBL69863 | NSC-365798 | US11866416, Example 8 | cid_667639 | piceatanol | trans-3,3',4,5'-tetrahydroxystilbene | ||
| Type | Small organic molecule | ||
| Emp. Form. | C14H12O4 | ||
| Mol. Mass. | 244.2427 | ||
| SMILES | Oc1cc(O)cc(\C=C\c2ccc(O)c(O)c2)c1 | ||
| Structure | 
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