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TargetCytochrome P450 1A1
LigandBDBM50239035
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1664950 (CHEMBL4014746)
IC50 4000±n/a nM
Citation Mohd Siddique, MUMcCann, GJSonawane, VRHorley, NGatchie, LJoshi, PBharate, SBJayaprakash, VSinha, BNChaudhuri, B Quinazoline derivatives as selective CYP1B1 inhibitors. Eur J Med Chem130:320-327 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cytochrome P450 1A1
Name:Cytochrome P450 1A1
Synonyms:CP1A1_HUMAN | CYP1A1 | CYPIA1 | Cytochrome P450 1A | Cytochrome P450 1A1 | Cytochrome P450 1A1 (CYP1A1) | P450 form 6 | P450-C | P450-P1
Type:Protein
Mol. Mass.:58177.23
Organism:Homo sapiens (Human)
Description:P04798
Residue:512
Sequence:
MLFPISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGKNPH
LALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQS
MSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAG
PGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLVNLNNNFGEVVGSGNPADFIPIL
RYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQEKQLDENANV
QLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLS
DRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKL
WVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEF
SVPLGVKVDMTPIYGLTMKHACCEHFQMQLRS
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BDBM50239035
n/a
NameBDBM50239035
Synonyms:CHEMBL4081914
TypeSmall organic molecule
Emp. Form.C15H12N2O3
Mol. Mass.268.2674
SMILESCOc1cc(ccc1O)-c1nc2ccccc2c(=O)[nH]1
Structure
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