Reaction Details |
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Target | 5-hydroxytryptamine receptor 2A |
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Ligand | BDBM82087 |
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Substrate/Competitor | n/a |
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Ki | 923±n/a nM |
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Comments | PDSP_172 |
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Citation | Nelson, DL; Lucaites, VL; Audia, JE; Nissen, JS; Wainscott, DB Species differences in the pharmacology of the 5-hydroxytryptamine2 receptor: structurally specific differentiation by ergolines and tryptamines. J Pharmacol Exp Ther265:1272-9 (1993) [PubMed] |
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More Info.: | Get all data from this article |
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5-hydroxytryptamine receptor 2A |
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Name: | 5-hydroxytryptamine receptor 2A |
Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2 | 5-HT2A | 5HT2A_PIG | HTR2A | Serotonin 2a (5-HT2a) receptor |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 52679.13 |
Organism: | PIG |
Description: | 5-HT2 0 0::P50129 |
Residue: | 470 |
Sequence: | MDVLCEENTSLSSPTNSFMQLNDDTRLYHNDFNSGEANTSDAFNWTVDSENRTNLSCEGC
LSPPCFSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHRRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGAL
LNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKS
SQLQTGQKENSKQDDKATENDCTMVALGKQHSEDAPADNSNTVNEKVSCV
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BDBM82087 |
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n/a |
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Name | BDBM82087 |
Synonyms: | 2-(5-methoxy-1H-indol-3-yl)ethanamine | 5-MT | 5-Methoxytryptamine hydrochloride | CAS_66-83-1 | tryptamine, 5-Methoxy |
Type | Small organic molecule |
Emp. Form. | C11H14N2O |
Mol. Mass. | 190.2417 |
SMILES | COc1ccc2[nH]cc(CCN)c2c1 |
Structure |
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