| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM84938 |
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| Substrate/Competitor | n/a |
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| Ki | 148±n/a nM |
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| Comments | PDSP_1133 |
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| Citation |  Nelson, DL; Lucaites, VL; Audia, JE; Nissen, JS; Wainscott, DB Species differences in the pharmacology of the 5-hydroxytryptamine2 receptor: structurally specific differentiation by ergolines and tryptamines. J Pharmacol Exp Ther265:1272-9 (1993) [PubMed] |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | 5-hydroxytryptamine receptor 2A |
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| Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2 | 5-HT2A | 5HT2A_PIG | HTR2A | Serotonin 2a (5-HT2a) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 52679.13 |
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| Organism: | PIG |
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| Description: | 5-HT2 0 0::P50129 |
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| Residue: | 470 |
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| Sequence: | MDVLCEENTSLSSPTNSFMQLNDDTRLYHNDFNSGEANTSDAFNWTVDSENRTNLSCEGC
LSPPCFSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHRRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGAL
LNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKS
SQLQTGQKENSKQDDKATENDCTMVALGKQHSEDAPADNSNTVNEKVSCV
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| BDBM84938 |
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| n/a |
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| Name | BDBM84938 |
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| Synonyms: | (6aR)-7-Methyl-4-isobutyl-4,6,6a真真,7,8,9,10,10a真真-octahydroindolo[4,3-fg]quinoline-9真真-carboxylic acid 2-hydroxy-1-methylpropyl ester 6-Methyl-1-(2-methylpropyl)ergoline-8真真-carboxylic acid 2-hydroxy-1-methylpropyl ester | (6aR)-7-Methyl-4-isobutyl-4,6,6a留,7,8,9,10,10a硫-octahydroindolo[4,3-fg]quinoline-9留-carboxylic acid 2-hydroxy-1-methylpropyl ester 6-Methyl-1-(2-methylpropyl)ergoline-8硫-carboxylic acid 2-hydroxy-1-methylpropyl ester | LY 197541 | LY-197541 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H34N2O3 |
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| Mol. Mass. | 398.5384 |
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| SMILES | CC(C)Cn1cc2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)OC(C)C(C)O)c3cccc1c23 |
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| Structure | 
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