| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-2B adrenergic receptor |
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| Ligand | BDBM84950 |
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| Substrate/Competitor | n/a |
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| Ki | >10000±n/a nM |
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| Comments | PDSP_1623 |
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| Citation |  Eglen, RM; Bonhaus, DW; Johnson, LG; Leung, E; Clark, RD Pharmacological characterization of two novel and potent 5-HT4 receptor agonists, RS 67333 and RS 67506, in vitro and in vivo. Br J Pharmacol115:1387-92 (1995) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Alpha-2B adrenergic receptor |
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| Name: | Alpha-2B adrenergic receptor |
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| Synonyms: | ADA2B_RAT | Adra2b | Adrenergic receptor alpha | Adrenergic receptor alpha-2 | Alpha-2B adrenergic receptor | Alpha-2B adrenoceptor | Alpha-2B adrenoreceptor | adrenergic Alpha2B |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 50379.83 |
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| Organism: | NEONATAL RAT |
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| Description: | adrenergic Alpha2B ADRA2B NEONATAL RAT::P19328 |
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| Residue: | 453 |
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| Sequence: | MSGPTMDHQEPYSVQATAAIASAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLA
AADILVATLIIPFSLANELLGYWYFWRAWCEVYLALDVLFCTSSIVHLCAISLDRYWAVS
RALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQRPEPRGLPQCELNQEAWYILA
SSIGSFFAPCLIMILVYLRIYVIAKRSHCRGLGAKRGSGEGESKKPQPVAGGVPTSAKVP
TLVSPLSSVGEANGHPKPPREKEEGETPEDPEARALPPTWSALPRSGQGQKKGTSGATAE
EGDEEDEEEVEECEPQTLPASPASVCNPPLQQPQTSRVLATLRGQVLLGKNVGVASGQWW
RRRTQLSREKRFTFVLAVVIGVFVVCWFPFFFSYSLGAICPQHCKVPHGLFQFFFWIGYC
NSSLNPVIYTVFNQDFRRAFRRILCRPWTQTGW
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| BDBM84950 |
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| n/a |
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| Name | BDBM84950 |
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| Synonyms: | CAS_183782 | NSC_183782 | RS 67333 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H29ClN2O2 |
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| Mol. Mass. | 352.899 |
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| SMILES | CCCCN1CCC(CCC(=O)c2cc(Cl)c(N)cc2OC)CC1 |
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| Structure | 
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