| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM78576 |
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| Substrate/Competitor | n/a |
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| Ki | 685±n/a nM |
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| Comments | PDSP_1850 |
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| Citation |  Tallman, JF; Primus, RJ; Brodbeck, R; Cornfield, L; Meade, R; Woodruff, K; Ross, P; Thurkauf, A; Gallager, DW I. NGD 94-1: identification of a novel, high-affinity antagonist at the human dopamine D4 receptor. J Pharmacol Exp Ther282:1011-9 (1997) [PubMed] |
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| More Info.: | Get all data from this article |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM78576 |
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| n/a |
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| Name | BDBM78576 |
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| Synonyms: | CIS-THIOTHIXENE | MLS000028463 | SMR000058396 | THIOTHIXENE | cid_941651 | med.21724, Compound Thiothixene |
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| Type | Small organic molecule |
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| Emp. Form. | C23H29N3O2S2 |
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| Mol. Mass. | 443.625 |
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| SMILES | CN(C)S(=O)(=O)c1ccc2Sc3ccccc3\C(=C\CCN3CCN(C)CC3)c2c1 |
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| Structure | 
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