| Reaction Details |
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 | Report a problem with these data |
| Target | Prostacyclin receptor |
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| Ligand | BDBM23954 |
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| Substrate/Competitor | n/a |
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| Ki | 11±n/a nM |
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| Comments | PDSP_965 |
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| Citation |  Kiriyama, M; Ushikubi, F; Kobayashi, T; Hirata, M; Sugimoto, Y; Narumiya, S Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol122:217-24 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Prostacyclin receptor |
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| Name: | Prostacyclin receptor |
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| Synonyms: | PI2R_MOUSE | Prostacyclin receptor | Prostaglandin I | Prostaglandin I2 | Ptgir |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44475.65 |
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| Organism: | MOUSE |
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| Description: | Prostaglandin I2 PTGIR MOUSE::P43252 |
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| Residue: | 415 |
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| Sequence: | MMASDGHPGPPSVTPGSPLSAGGREWQGMAGSCWNITYVQDSVGPATSTLMFVAGVVGNG
LALGILGARRRSHPSAFAVLVTGLAVTDLLGTCFLSPAVFVAYARNSSLLGLAHGGTMLC
DTFAFAMTFFGLASTLILFAMAVERCLALSHPYLYAQLDGPRCARFALPSIYAFCCLFCS
LPLLGLGEHQQYCPGSWCFIRMRSAQPGGCAFSLAYASLMALLVTSIFFCNGSVTLSLYH
MYRQQRRHHGSFVPTSRAREDEVYHLILLALMTVIMAVCSLPLMIRGFTQAIAPDSREMG
DLLAFRFNAFNPILDPWVFILFRKAVFQRLKFWLCCLCARSVHGDLQAPLSRPASGRRDP
PAPTSLQAKEGSWVPLSSWGTGQVAPLTAVPLTGGDGCSVGMPSKSEAIAACSLC
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| BDBM23954 |
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| n/a |
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| Name | BDBM23954 |
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| Synonyms: | 5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-octahydropentalen-2-ylidene]pentanoic acid | CHEMBL494 | ILOPROST | Ventavis | [3H]-Iloprost |
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| Type | radiolabeled ligand |
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| Emp. Form. | C22H32O4 |
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| Mol. Mass. | 360.4871 |
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| SMILES | [H][C@]12C[C@@H](O)[C@H](\C=C\[C@@H](O)C(C)CC#CC)[C@@]1([H])C\C(C2)=C\CCCC(O)=O |
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| Structure | 
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