| Reaction Details |
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 | Report a problem with these data |
| Target | Thromboxane-A synthase |
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| Ligand | BDBM50008781 |
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| Substrate/Competitor | n/a |
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| Ki | 13±n/a nM |
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| Comments | PDSP_1747 |
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| Citation |  Kiriyama, M; Ushikubi, F; Kobayashi, T; Hirata, M; Sugimoto, Y; Narumiya, S Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol122:217-24 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Thromboxane-A synthase |
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| Name: | Thromboxane-A synthase |
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| Synonyms: | Cyp5 | Cyp5a1 | THAS_MOUSE | Tbxas1 | Thromboxane Alpha |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 60395.39 |
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| Organism: | MOUSE |
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| Description: | Thromboxane Alpha 0 MOUSE::P36423 |
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| Residue: | 533 |
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| Sequence: | MEVLGLLKFEVSGTIVTVTLLVALLALLKWYSMSAFSRLEKLGIRHPKPSPFVGNLMFFR
QGFWESQLELRERYGPLCGYYLGRRMHVVISEPDMIKQVLVENFSNFSNRMASGLEPKMV
ADSVLLLRDRRWEEVRGALMSSFSPEKLDEMTPLISQACELLVAHLKRYAASRDAFNIQR
CYCCYTIDVVASVAFGTQVDSQNSPEDPFVQHCRRASTFCIPRPLLVLILSFPSIMVPLA
RILPNKNRDELNGFFNTLIRNVIALRDQQAAEERRRDFLQMVLDAQHSMNSVGVEGFDMV
PESLSSSECTKEPPQRCHPTSTSKPFTVDEIVGQAFLFLIAGHEVITNTLSFITYLLATH
PDCQERLLKEVDLFMGKHPAPEYHSLQEGLPYLDMVISETLRMYPPAFRFTREAAQDCEV
LGQRIPAGTVLEIAVGALHHDPEHWPNPETFDPERFTAEARLQRRPFTYLPFGAGPRSCL
GVRLGLLVVKLTILQVLHKFRFEASPETQVPLQLESKSALGPKNGVYIKIVSR
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| BDBM50008781 |
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| n/a |
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| Name | BDBM50008781 |
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| Synonyms: | 7-(3-(2-ethyl-N-phenylhydrazinecarboxamide)-7-oxa-bicyclo[2.2.1]hept-2-yl)-hept-5-enoic acid | CHEMBL286330 | SQ 29548 | SQ-29548 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H29N3O4 |
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| Mol. Mass. | 387.4727 |
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| SMILES | OC(=O)CCC\C=C/C[C@H]1[C@@H]2CCC(O2)[C@H]1CNNC(=O)Nc1ccccc1 |
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| Structure | 
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