| Reaction Details |
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 | Report a problem with these data |
| Target | Neuronal acetylcholine receptor subunit alpha-2 |
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| Ligand | BDBM81458 |
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| Substrate/Competitor | n/a |
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| Ki | 2260±n/a nM |
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| Comments | PDSP_761 |
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| Citation |  Stauderman, KA; Mahaffy, LS; Akong, M; Veliçelebi, G; Chavez-Noriega, LE; Crona, JH; Johnson, EC; Elliott, KJ; Gillespie, A; Reid, RT; Adams, P; Harpold, MM; Corey-Naeve, J Characterization of human recombinant neuronal nicotinic acetylcholine receptor subunit combinations alpha2beta4, alpha3beta4 and alpha4beta4 stably expressed in HEK293 cells. J Pharmacol Exp Ther284:777-89 (1998) [PubMed] |
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| More Info.: | Get all data from this article |
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| Neuronal acetylcholine receptor subunit alpha-2 |
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| Name: | Neuronal acetylcholine receptor subunit alpha-2 |
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| Synonyms: | ACHA2_HUMAN | CHRNA2 | Neuronal acetylcholine receptor; alpha2/beta2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 59759.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Cholinergic, Nicotinic Alpha2Beta2 0 HUMAN::Q15822 |
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| Residue: | 529 |
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| Sequence: | MGPSCPVFLSFTKLSLWWLLLTPAGGEEAKRPPPRAPGDPLSSPSPTALPQGGSHTETED
RLFKHLFRGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKL
RWNPTDFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYK
SSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTVDLKDYWESGEWAIVNATGTY
NSKKYDCCAEIYPDVTYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLC
ISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTH
TMPHWVRGALLGCVPRWLLMNRPPPPVELCHPLRLKLSPSYHWLESNVDAEEREVVVEEE
DRWACAGHVAPSVGTLCSHGHLHSGASGPKAEALLQEGELLLSPHMQKALEGVHYIADHL
RSEDADSSVKEDWKYVAMVIDRIFLWLFIIVCFLGTIGLFLPPFLAGMI
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| BDBM81458 |
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| n/a |
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| Name | BDBM81458 |
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| Synonyms: | CAS_57-94-3 | NSC_6000 | d-Tubocurarine |
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| Type | Small organic molecule |
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| Emp. Form. | C37H41N2O6 |
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| Mol. Mass. | 609.7307 |
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| SMILES | COc1cc2CC[N+](C)(C)C3Cc4ccc(O)c(Oc5cc6C(Cc7ccc(Oc(c1O)c23)cc7)N(C)CCc6cc5OC)c4 |
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| Structure | 
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