| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-2A adrenergic receptor |
|---|
| Ligand | BDBM25392 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | >10000±n/a nM |
|---|
| Comments | PDSP_6116 |
|---|
| Citation |  Jasper, JR; Lesnick, JD; Chang, LK; Yamanishi, SS; Chang, TK; Hsu, SA; Daunt, DA; Bonhaus, DW; Eglen, RM Ligand efficacy and potency at recombinant alpha2 adrenergic receptors: agonist-mediated [35S]GTPgammaS binding. Biochem Pharmacol55:1035-43 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Alpha-2A adrenergic receptor |
|---|
| Name: | Alpha-2A adrenergic receptor |
|---|
| Synonyms: | ADRA2A | Alpha-2A adrenergic receptor | adrenergic Alpha2A |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 48888.08 |
|---|
| Organism: | MOUSE |
|---|
| Description: | adrenergic Alpha2A ADRA2A MOUSE::Q01338 |
|---|
| Residue: | 450 |
|---|
| Sequence: | MGSLQPDAGNSSWNGTEAPGGGTRATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFT
SRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKVWCEIYLALDVLFCTSS
IVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISIEKKGAGGG
QQPAEPSCKINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDACS
APPGGADRRPNGLGPERGAGPTGAEAEPLPTQLNGAPGEPAPAGPRDGDALDLEESSSSE
HAERPPGPRRPDRGPRAKGKTRASQVKPGDSLPRRGPGAAGPGASGSGHGEERGGGAKAS
RWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLIAVGCPVPSQLFNFFFWFGYCNSS
LNPVIYTIFNHDFRRAFKKILCRGDRKRIV
|
|
|
|---|
| BDBM25392 |
|---|
| n/a |
|---|
| Name | BDBM25392 |
|---|
| Synonyms: | 4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;hydrochloride | 4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol | 4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,2-diol, 2 | CHEMBL434 | ISOPROTERONOL | Isoprenaline | Isoproterenol | Isoproterenol (-) | Isoproterenol,(+) | Isoproterenol-l | Norisodrine | Novodrin |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H17NO3 |
|---|
| Mol. Mass. | 211.2576 |
|---|
| SMILES | CC(C)NCC(O)c1ccc(O)c(O)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
